Assessment of Structural Intolerance and Durability
General Structure Information 2xqq DYNLL2 human dynein light chain (dynll2) in complex with an in vitro evolved peptide (ac-srgtqte). 1.31Å AUTH P.RAPALI,L.RADNAI,D.SUVEGES,V.HARMAT,F.TOLGYESI,AUTH 2 W.Y.WAHLGREN,G.KATONA,L.NYITRAY,G.PALTITL DIRECTED EVOLUTION REVEALS THE BINDING MOTIF PREFERENCE OFTITL 2 THE LC8/DYNLL HUB PROTEIN AND PREDICTS LARGE NUMBERS OFTITL 3 NOVEL BINDERS IN THE HUMAN PROTEOMEREF PLOS ONE V. 6 18818 2011REFN […]
General Structure Information 4ddg OTUB1 crystal structure of human otub1/ubch5b~ub/ub 3.3Å AUTH Y.C.JUANG,M.C.LANDRY,M.SANCHES,V.VITTAL,C.C.LEUNG,AUTH 2 D.F.CECCARELLI,A.R.MATEO,J.N.PRUNEDA,D.Y.MAO,R.K.SZILARD,AUTH 3 S.ORLICKY,M.MUNRO,P.S.BRZOVIC,R.E.KLEVIT,F.SICHERI,AUTH 4 D.DUROCHERTITL OTUB1 CO-OPTS LYS48-LINKED UBIQUITIN RECOGNITION TO SUPPRESSTITL 2 E2 ENZYME FUNCTION.REF MOL.CELL V. 45 384 2012REFN ISSN 1097-2765PMID 22325355DOI 10.1016/J.MOLCEL.2012.01.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2egm TRIM41 solution structure of the zf-b_box domain from human tripartite motif protein 41 -1.0Å AUTH K.INOUE,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-B_BOX DOMAIN FROMTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN 41REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mxo PGAM5 crystal structure oh human phosphoglycerate mutase family member 5 (pgam5) 1.7Å AUTH A.CHAIKUAD,I.ALFANO,S.PICAUD,P.FILIPPAKOPOULOS,A.BARR,AUTH 2 F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,AUTH 3 K.TAKEDA,H.ICHIJO,S.KNAPPTITL CRYSTAL STRUCTURE OH HUMAN PHOSPHOGLYCERATE MUTASE FAMILYTITL 2 MEMBER 5 (PGAM5)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ct7 RNF31 solution structure of the ibr domain of the ring finger protein 31 protein -1.0Å AUTH K.MIYAMOTO,S.KOSHIBA,T.TOMIZAWA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IBR DOMAIN OF THE RINGTITL 2 FINGER PROTEIN 31 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmf RNF25 an extended conformation of the rwd domain of human ring finger protein 25 -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,S.WATABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL AN EXTENDED CONFORMATION OF THE RWD DOMAIN OFTITL 2 HUMAN RING FINGER PROTEIN 25REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3qc3 RPE crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699) from homo sapiens at 2.20 a resolution 2.2Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)TITL CRYSTAL STRUCTURE OF A D-RIBULOSE-5-PHOSPHATE-3-EPIMERASETITL 2 (NP_954699) FROM HOMO SAPIENS AT 2.20 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3aqg ZG16B crystal structure of human pancreatic secretory protein zg16b 2.75Å AUTH M.KANAGAWA,T.SATOH,A.IKEDA,Y.NAKANO,H.YAGI,K.KATO,AUTH 2 K.KOJIMA-AIKAWA,Y.YAMAGUCHITITL CRYSTAL STRUCTURES OF HUMAN SECRETORY PROTEINS ZG16P ANDTITL 2 ZG16B REVEAL A JACALIN-RELATED BETA-PRISM FOLDREF BIOCHEM.BIOPHYS.RES.COMMUN. 2010REFN ESSN 1090-2104PMID 21110947DOI 10.1016/J.BBRC.2010.11.093 Variant Set Distributions Mapped Variants
General Structure Information 2nn6 EXOSC8 structure of the human rna exosome composed of rrp41, rrp45, rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40 3.35Å AUTH Q.LIU,J.C.GREIMANN,C.D.LIMATITL RECONSTITUTION, ACTIVITIES, AND STRUCTURE OF THETITL 2 EUKARYOTIC RNA EXOSOME.REF CELL(CAMBRIDGE,MASS.) V. 127 1223 2006REFN ISSN 0092-8674PMID 17174896DOI 10.1016/J.CELL.2006.10.037 Variant Set Distributions Mapped Variants
General Structure Information 3al2 TOPBP1 crystal structure of topbp1 brct7/8 2.0Å AUTH C.C.LEUNG,Z.GONG,J.CHEN,J.N.GLOVERTITL MOLECULAR BASIS OF BACH1/FANCJ RECOGNITION BY TOPBP1 IN DNATITL 2 REPLICATION CHECKPOINT CONTROLREF J.BIOL.CHEM. V. 286 4292 2011REFN ISSN 0021-9258PMID 21127055DOI 10.1074/JBC.M110.189555 Variant Set Distributions Mapped Variants