General Structure Information
| PDB ID | 3al2 |
| HGNC Gene Label(s) | TOPBP1 |
| Structure Name | crystal structure of topbp1 brct7/8 |
| Resolution | 2.0Å |
| Reference | AUTH C.C.LEUNG,Z.GONG,J.CHEN,J.N.GLOVERTITL MOLECULAR BASIS OF BACH1/FANCJ RECOGNITION BY TOPBP1 IN DNATITL 2 REPLICATION CHECKPOINT CONTROLREF J.BIOL.CHEM. V. 286 4292 2011REFN ISSN 0021-9258PMID 21127055DOI 10.1074/JBC.M110.189555 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 218 |
| Number Of SNVs | 33 |
| Number Of Permutations | 17047 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.008 |
| p-value | 0.052 |