Assessment of Structural Intolerance and Durability
General Structure Information 3bc1 SYTL2 crystal structure of the complex rab27a-slp2a 1.8Å AUTH L.M.G.CHAVAS,K.IHARA,M.KAWASAKI,S.TORII,T.UEJIMA,R.KATO,AUTH 2 T.IZUMI,S.WAKATSUKITITL ELUCIDATION OF RAB27 RECRUITMENT BY ITS EFFECTORS: STRUCTURETITL 2 OF RAB27A BOUND TO EXOPHILIN4/SLP2-AREF STRUCTURE V. 16 1468 2008REFN ISSN 0969-2126PMID 18940603DOI 10.1016/J.STR.2008.07.015 Variant Set Distributions Mapped Variants
General Structure Information 4h3k SSU72 crystal structure of a ternary complex of human symplekin ntd, human ssu72 and a rna polymerase ii ctd peptide phosphorylated at ser-2, ser-5 and ser-7 2.0Å AUTH K.XIANG,J.L.MANLEY,L.TONGTITL AN UNEXPECTED BINDING MODE FOR A POL II CTD PEPTIDETITL 2 PHOSPHORYLATED AT SER7 IN THE ACTIVE SITE OF THE CTDTITL 3 […]
General Structure Information 4bn2 KIF15 the crystal structure of kinesin-like protein kif15 2.7Å AUTH M.KLEJNOT,A.FALNIKAR,V.ULAGANATHAN,R.A.CROSS,P.W.BAAS,AUTH 2 F.KOZIELSKITITL THE CRYSTAL STRUCTURE AND BIOCHEMICAL CHARACTERIZATION OFTITL 2 KIF15: A BIFUNCTIONAL MOLECULAR MOTOR INVOLVED IN BIPOLARTITL 3 SPINDLE FORMATION AND NEURONAL DEVELOPMENTREF ACTA CRYSTALLOGR.,SECT.D V. 70 123 2014REFN ISSN 0907-4449PMID 24419385DOI 10.1107/S1399004713028721 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3ep0 PRDM12 methyltransferase domain of human pr domain-containing protein 12 2.1Å AUTH H.ZENG,M.F.AMAYA,P.LOPPNAU,J.MIN,A.N.PLOTNIKOV,H.WUTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAINTITL 2 OF HUMAN PR DOMAIN-CONTAINING PROTEIN 12.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l08 UPF3A solution nmr structure of nonsense mrna reducing factor 3a from h. sapiens, northeast structural genomics consortium target hr4714b -1.0Å AUTH R.MANI,L.MAO,C.CICCOSANTI,R.SHASTRY,T.B.ACTON,R.XIAO,AUTH 2 G.V.T.SWAPNA,J.K.EVERETT,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF NONSENSE MRNA REDUCING FACTOR 3ATITL 2 FROM H. SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUMTITL 3 TARGET HR4714BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2fp0 ADPRHL2 human adp-ribosylhydrolase 3 2.05Å AUTH C.MUELLER-DIECKMANN,S.KERNSTOCK,M.LISUREK,J.P.VON KRIES,AUTH 2 F.HAAG,M.S.WEISS,F.KOCH-NOLTETITL THE STRUCTURE OF HUMAN ADP-RIBOSYLHYDROLASE 3 (ARH3)TITL 2 PROVIDES INSIGHTS INTO THE REVERSIBILITY OF PROTEINTITL 3 ADP-RIBOSYLATION.REF PROC.NATL.ACAD.SCI.USA V. 103 15026 2006REFN ISSN 0027-8424PMID 17015823DOI 10.1073/PNAS.0606762103 Variant Set Distributions Mapped Variants
General Structure Information 2i7k BRD7 solution structure of the bromodomain of human brd7 protein -1.0Å AUTH H.SUN,J.LIU,J.ZHANG,W.SHEN,H.HUANG,C.XU,H.DAI,J.WU,AUTH 2 Y.SHITITL SOLUTION STRUCTURE OF BRD7 BROMODOMAIN AND ITSTITL 2 INTERACTION WITH ACETYLATED PEPTIDES FROM HISTONETITL 3 H3 AND H4REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 358 435 2007REFN ISSN 0006-291XPMID 17498659DOI 10.1016/J.BBRC.2007.04.139 Variant Set Distributions Mapped Variants
General Structure Information 4iej DMAP1 crystal structure of a dna methyltransferase 1 associated protein 1 (dmap1) from homo sapiens at 1.45 a resolution 1.45Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A DNA METHYLTRANSFERASE 1 ASSOCIATEDTITL 2 PROTEIN 1 (DMAP1) FROM HOMO SAPIENS AT 1.45 A RESOLUTIONREF […]
General Structure Information 2m0r S100A14 solution structure and dynamics of human s100a14 -1.0Å AUTH I.BERTINI,V.BORSI,L.CEROFOLINI,S.DAS GUPTA,M.FRAGAI,AUTH 2 C.LUCHINATTITL SOLUTION STRUCTURE AND DYNAMICS OF HUMAN S100A14.REF J.BIOL.INORG.CHEM. V. 18 183 2013REFN ISSN 0949-8257PMID 23197251DOI 10.1007/S00775-012-0963-3 Variant Set Distributions Mapped Variants
General Structure Information 2pz1 ARHGEF4 crystal structure of auto-inhibited asef 2.25Å AUTH N.MITIN,L.BETTS,M.E.YOHE,C.J.DER,J.SONDEK,K.L.ROSSMANTITL RELEASE OF AUTOINHIBITION OF ASEF BY APC LEADS TO CDC42TITL 2 ACTIVATION AND TUMOR SUPPRESSION.REF NAT.STRUCT.MOL.BIOL. V. 14 814 2007REFN ISSN 1545-9993PMID 17704816DOI 10.1038/NSMB1290 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants