3EP0.A | PRDM12

PDB ID	3ep0
HGNC Gene Label(s)	PRDM12
Structure Name	methyltransferase domain of human pr domain-containing protein 12
Resolution	2.1Å
Reference	AUTH H.ZENG,M.F.AMAYA,P.LOPPNAU,J.MIN,A.N.PLOTNIKOV,H.WUTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAINTITL 2 OF HUMAN PR DOMAIN-CONTAINING PROTEIN 12.REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
9:133542054		I>L	A:36	(7.19, 45.54, 18.00)
9:133542072		G>R	A:42	(7.49, 36.62, 16.63)
9:133542075		I>V	A:43	(4.68, 34.02, 17.75)
9:133542138		A>S	A:64	(14.45, 33.68, 43.79)
9:133542139	COSM487127	A>V	A:64	(14.45, 33.68, 43.79)
9:133542142		P>Q	A:65	(12.28, 35.79, 45.46)
9:133543552	rs572272341	N>S	A:82	(2.21, 31.42, 47.10)
9:133543555	rs148215906	E>G	A:83	(-3.14, 29.74, 48.56)
9:133543560	rs141272501	G>S	A:85	(-0.40, 35.91, 46.39)
9:133543564	rs147403234	T>M	A:86	(2.63, 35.75, 47.85)
9:133543570	rs139807684	R>H	A:88	(6.35, 29.55, 46.09)
9:133543575		F>L	A:90	(10.42, 35.17, 39.79)
9:133543581	COSM1105987	D>N	A:92	(14.30, 33.14, 33.75)
9:133543585		A>V	A:93	(13.89, 32.07, 30.04)
9:133543612		M>K	A:102	(6.38, 29.83, 24.61)
9:133543632	COSM1105988	R>C	A:109	(2.68, 47.68, 23.76)
9:133543636		N>S	A:110	(-1.78, 47.34, 25.79)
9:133543638	COSM171967	E>K	A:111	(-6.30, 44.68, 28.06)
9:133543662		V>F	A:119	(-2.32, 30.58, 33.38)
9:133543668	rs375684006	I>V	A:121	(-1.50, 24.84, 35.99)
9:133543677		S>G	A:124	(3.08, 25.42, 36.04)
9:133543680		I>V	A:125	(3.49, 29.15, 33.80)
9:133543696		I>T	A:130	(-8.21, 36.02, 26.35)
9:133553917		M>T	A:132	(-10.39, 34.26, 19.32)
9:133553952	rs375887892	G>R	A:144	(-4.28, 38.77, 34.21)
9:133553955		N>D	A:145	(-6.97, 39.64, 36.48)

3EP0.A | PRDM12.