4H3K.E | SSU72

General Structure Information

PDB ID 4h3k
HGNC Gene Label(s) SSU72
Structure Name crystal structure of a ternary complex of human symplekin ntd, human ssu72 and a rna polymerase ii ctd peptide phosphorylated at ser-2, ser-5 and ser-7
Resolution 2.0Å
Reference AUTH K.XIANG,J.L.MANLEY,L.TONGTITL AN UNEXPECTED BINDING MODE FOR A POL II CTD PEPTIDETITL 2 PHOSPHORYLATED AT SER7 IN THE ACTIVE SITE OF THE CTDTITL 3 PHOSPHATASE SSU72.REF GENES DEV. V. 26 2265 2012REFN ISSN 0890-9369PMID 23070812DOI 10.1101/GAD.198853.112

Variant Set Distributions

ExAC Variants

Number Of Residues 190
Number Of SNVs 18
Number Of Permutations 7727
Optimal Distance Threshold 6.0
K Statistic 0.013
p-value 0.805

Mapped Variants

[+] ExAC Missense Variants