Assessment of Structural Intolerance and Durability
General Structure Information 2csf SATB2 solution structure of the second cut domain of human satb2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND CUT DOMAIN OFTITL 2 HUMAN SATB2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tg5 SMYD2 structure of smyd2 in complex with p53 and sah 2.3Å AUTH L.WANG,L.LI,H.ZHANG,X.LUO,J.DAI,S.ZHOU,J.GU,J.ZHU,P.ATADJA,AUTH 2 C.LU,E.LI,K.ZHAOTITL STRUCTURE OF HUMAN SMYD2 REVEALS THE BASIS OF P53 TUMORTITL 2 SUPPRESSOR METHYLATIONREF J.BIOL.CHEM. 2011REFN ESSN 1083-351XPMID 21880715DOI 10.1074/JBC.M111.262410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3mop IRAK4 the ternary death domain complex of myd88, irak4, and irak2 3.4Å AUTH S.C.LIN,Y.C.LO,H.WUTITL HELICAL ASSEMBLY IN THE MYD88-IRAK4-IRAK2 COMPLEX INTITL 2 TLR/IL-1R SIGNALLING.REF NATURE V. 465 885 2010REFN ISSN 0028-0836PMID 20485341DOI 10.1038/NATURE09121 Variant Set Distributions Mapped Variants
General Structure Information 2m3d DDX21 nmr structure of the guct domain from human dead box polypeptide 21 -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICHTITL NMR STRUCTURE OF THE GUCT DOMAIN FROM HUMAN DEAD BOXTITL 2 POLYPEPTIDE 21 (DDX21)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zyj LRRC4C netring1 in complex with ngl1 3.25Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3nwn KIF9 crystal structure of the human kif9 motor domain in complex with adp 2.0Å AUTH H.ZHU,W.TEMPEL,H.HE,Y.SHEN,J.WANG,G.BROTHERS,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE HUMAN KIF9 MOTOR DOMAIN IN COMPLEXTITL 2 WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2a8j TASP1 crystal structure of human taspase1 (acivated form) 1.9Å AUTH J.A.KHAN,B.M.DUNN,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN TASPASE1, A CRUCIALTITL 2 PROTEASE REGULATING THE FUNCTION OF MLL.REF STRUCTURE V. 13 1443 2005REFN ISSN 0969-2126PMID 16216576DOI 10.1016/J.STR.2005.07.006 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2err RBFOX1 nmr structure of the rna binding domain of human fox-1 in complex with ugcaugu -1.0Å AUTH S.D.AUWETER,R.FASAN,L.REYMOND,J.G.UNDERWOOD,AUTH 2 D.L.BLACK,S.PITSCH,F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION BY THE HUMANTITL 2 ALTERNATIVE SPLICING FACTOR FOX-1.REF EMBO J. V. 25 163 2006REFN ISSN 0261-4189PMID 16362037DOI 10.1038/SJ.EMBOJ.7600918 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4c9b CWC22 crystal structure of eif4aiii-cwc22 complex 2.0Å AUTH G.BUCHWALD,S.SCHUESSLER,C.BASQUIN,H.LE HIR,E.CONTITITL CRYSTAL STRUCTURE OF THE HUMAN EIF4AIII-CWC22 COMPLEX SHOWSTITL 2 HOW A DEAD-BOX PROTEIN IS INHIBITED BY A MIF4G DOMAINREF PROC.NATL.ACAD.SCI.USA V. 110 E4611 2013REFN ISSN 0027-8424PMID 24218557DOI 10.1073/PNAS.1314684110 Variant Set Distributions Mapped Variants
General Structure Information 3nhb ABCB6 nucleotide binding domain of human abcb6 (adp bound structure) 2.15Å AUTH M.HAFFKE,A.MENZEL,Y.CARIUS,D.JAHN,D.W.HEINZTITL STRUCTURES OF THE NUCLEOTIDE-BINDING DOMAIN OF THE HUMANTITL 2 ABCB6 TRANSPORTER AND ITS COMPLEXES WITH NUCLEOTIDES.REF ACTA CRYSTALLOGR.,SECT.D V. 66 979 2010REFN ISSN 0907-4449PMID 20823549DOI 10.1107/S0907444910028593 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]