Assessment of Structural Intolerance and Durability
General Structure Information 4gul PIR study on structure and function relationships in human ferric pirin 1.8Å AUTH F.LIU,I.REHMANI,S.ESAKI,R.FU,L.CHEN,V.DE SERRANO,A.LIUTITL PIRIN IS AN IRON-DEPENDENT REDOX REGULATOR OF NF-KAPPA B.REF PROC.NATL.ACAD.SCI.USA V. 110 9722 2013REFN ISSN 0027-8424PMID 23716661DOI 10.1073/PNAS.1221743110 Variant Set Distributions Mapped Variants
General Structure Information 3gid ACACB the biotin carboxylase (bc) domain of human acetyl-coa carboxylase 2 (acc2) in complex with soraphen a 2.3Å AUTH B.RAYMER,M.KAVANA,A.PRICE,B.WANG,L.CORCORAN,R.KULATHILA,AUTH 2 J.GROARKE,T.MANNTITL SYNTHESIS AND CHARACTERIZATION OF A BODIPY-LABELEDTITL 2 DERIVATIVE OF SORAPHEN A THAT BINDS TO ACETYL-COATITL 3 CARBOXYLASE.REF BIOORG.MED.CHEM.LETT. V. 19 2804 2009REFN ISSN 0960-894XPMID 19359168DOI 10.1016/J.BMCL.2009.03.107 Variant Set Distributions […]
General Structure Information 2l4n CCL21 solution structure of the chemokine ccl21 -1.0Å AUTH M.LOVE,J.L.SANDBERG,J.J.ZIAREK,K.P.GERARDEN,R.R.RODE,AUTH 2 D.R.JENSEN,D.R.MCCASLIN,F.C.PETERSON,C.T.VELDKAMPTITL SOLUTION STRUCTURE OF CCL21 AND IDENTIFICATION OF A PUTATIVETITL 2 CCR7 BINDING SITE.REF BIOCHEMISTRY V. 51 733 2012REFN ISSN 0006-2960PMID 22221265DOI 10.1021/BI201601K Variant Set Distributions Mapped Variants
General Structure Information 2dls ARHGEF11 solution structure of the pdz domain of human rho guanine nucleotide exchange factor 11 -1.0Å AUTH K.INOUE,T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN OF HUMAN RHOTITL 2 GUANINE NUCLEOTIDE EXCHANGE FACTOR 11REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mft CASK cask-4m cam kinase domain, mn2+ 2.2Å AUTH K.MUKHERJEE,M.SHARMA,R.JAHN,M.C.WAHL,T.C.SUDHOFTITL EVOLUTION OF CASK INTO A MG2+-SENSITIVE KINASE.REF SCI.SIGNAL. V. 3 RA33 2010REFN ESSN 1937-9145PMID 20424264DOI 10.1126/SCISIGNAL.2000800 Variant Set Distributions Mapped Variants
General Structure Information 3t0o RNASET2 crystal structure analysis of human rnase t2 1.59Å AUTH A.THORN,R.STEINFELD,M.ZIEGENBEIN,M.GRAPP,H.H.HSIAO,H.URLAUB,AUTH 2 G.M.SHELDRICK,J.GARTNER,R.KRATZNERTITL STRUCTURE AND ACTIVITY OF THE ONLY HUMAN RNASE T2.REF NUCLEIC ACIDS RES. V. 40 8733 2012REFN ISSN 0305-1048PMID 22735700DOI 10.1093/NAR/GKS614 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2dmg ESYT2 solution structure of the third c2 domain of kiaa1228 protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD C2 DOMAIN OFTITL 2 KIAA1228 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1xnj PAPSS1 aps complex of human paps synthetase 1 1.98Å AUTH S.HARJES,P.BAYER,A.J.SCHEIDIGTITL THE CRYSTAL STRUCTURE OF HUMAN PAPS SYNTHETASE 1 REVEALSTITL 2 ASYMMETRY IN SUBSTRATE BINDINGREF J.MOL.BIOL. V. 347 623 2005REFN ISSN 0022-2836PMID 15755455DOI 10.1016/J.JMB.2005.01.005 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1s1n NPHP1 sh3 domain of human nephrocystin -1.0Å AUTH A.LE MAIRE,T.WEBER,S.SAUNIER,I.BROUTIN,C.ANTIGNAC,AUTH 2 A.DUCRUIX,F.DARDELTITL SOLUTION NMR STRUCTURE OF THE SH3 DOMAIN OF HUMANTITL 2 NEPHROCYSTIN AND ANALYSIS OF A MUTATION-CAUSINGTITL 3 JUVENILE NEPHRONOPHTHISIS.REF PROTEINS V. 59 347 2005REFN ISSN 0887-3585PMID 15723349DOI 10.1002/PROT.20344 Variant Set Distributions Mapped Variants
General Structure Information 3d8f APBB1 crystal structure of the human fe65-ptb1 domain with bound phosphate (trigonal crystal form) 2.7Å AUTH J.RADZIMANOWSKI,S.RAVAUD,S.SCHLESINGER,J.KOCH,AUTH 2 K.BEYREUTHER,I.SINNING,K.WILDTITL CRYSTAL STRUCTURE OF THE HUMAN FE65-PTB1 DOMAIN.REF J.BIOL.CHEM. V. 283 23113 2008REFN ISSN 0021-9258PMID 18550529DOI 10.1074/JBC.M800861200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants