General Structure Information
| PDB ID | 3mft |
| HGNC Gene Label(s) | CASK |
| Structure Name | cask-4m cam kinase domain, mn2+ |
| Resolution | 2.2Å |
| Reference | AUTH K.MUKHERJEE,M.SHARMA,R.JAHN,M.C.WAHL,T.C.SUDHOFTITL EVOLUTION OF CASK INTO A MG2+-SENSITIVE KINASE.REF SCI.SIGNAL. V. 3 RA33 2010REFN ESSN 1937-9145PMID 20424264DOI 10.1126/SCISIGNAL.2000800 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 302 |
| Number Of SNVs | 16 |
| Number Of Permutations | 2558 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.192 |
| p-value | 0.114 |
ClinVar
| Number Of Residues | 302 |
| Number Of SNVs | 4 |
| Number Of Permutations | 431 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.333 |
| p-value | 0.649 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.217 |
| p-value | 0.484 |