Assessment of Structural Intolerance and Durability
General Structure Information 2iqj SMAP2 crystal structure of the gap domain of smap1l (loc64744) stromal membrane-associated protein 1-like 1.9Å AUTH Y.TONG,S.DIMOV,L.SHEN,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL STRUCTURE OF THE GAP DOMAIN OF SMAP1L (LOC64744)TITL 2 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1-LIKEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1ey2 HGD human homogentisate dioxygenase with fe(ii) 2.3Å AUTH G.P.TITUS,H.A.MUELLER,J.BURGNER,S.RODRIGUEZ DE CORDOBA,AUTH 2 M.A.PENALVA,D.E.TIMMTITL CRYSTAL STRUCTURE OF HUMAN HOMOGENTISATE DIOXYGENASE.REF NAT.STRUCT.BIOL. V. 7 542 2000REFN ISSN 1072-8368PMID 10876237DOI 10.1038/76756 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4f7h FERMT2 the crystal structure of kindlin-2 pleckstrin homology domain in free form 1.9Å AUTH Y.LIU,Y.ZHU,S.YE,R.ZHANGTITL CRYSTAL STRUCTURE OF KINDLIN-2 PH DOMAIN REVEALS ATITL 2 CONFORMATIONAL TRANSITION FOR ITS MEMBRANE ANCHORING ANDTITL 3 REGULATION OF INTEGRIN ACTIVATION.REF PROTEIN CELL V. 3 434 2012REFN ISSN 1674-800XPMID 22653426DOI 10.1007/S13238-012-2046-1 Variant Set Distributions Mapped Variants
General Structure Information 2i1n DLG3 crystal structure of the 1st pdz domain of human dlg3 1.85Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,C.PHILLIPS,AUTH 2 C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINED WITH THETITL 2 HELP OF SELF-BINDING C-TERMINAL EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 4juy RNF31 crystal structure of the pub domain of e3 ubiquitin ligase rnf31 2.4Å AUTH J.HU,A.DONG,Y.LI,A.WERNIMONT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,Y.TONGTITL CRYSTAL STRUCTURE OF THE PUB DOMAIN OF E3 UBIQUITIN LIGASETITL 2 RNF31REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2vx2 ECHDC3 crystal structure of human enoyl coenzyme a hydratase domain-containing protein 3 (echdc3) 2.3Å AUTH W.W.YUE,K.GUO,G.KOCHAN,E.PILKA,J.W.MURRAY,E.SALAH,R.COCKING,AUTH 2 Z.SUN,A.K.ROOS,A.C.W.PIKE,P.FILIPPAKOPOULOS,C.ARROWSMITH,AUTH 3 M.WIKSTROM,A.EDWARDS,C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN ENOYL COENZYME A HYDRATASETITL 2 DOMAIN-CONTAINING PROTEIN 3 (ECHDC3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ytw HTRA1 solution structure of the pdz-domain of human protease htra 1 precursor -1.0Å AUTH A.K.GORONCY,K.SAITO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ-DOMAIN OF HUMANTITL 2 PROTEASE HTRA 1 PRECURSORREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1tdh NEIL1 crystal structure of human endonuclease viii-like 1 (neil1) 2.1Å AUTH S.DOUBLIE,V.BANDARU,J.P.BOND,S.S.WALLACETITL THE CRYSTAL STRUCTURE OF HUMAN ENDONUCLEASETITL 2 VIII-LIKE 1 (NEIL1) REVEALS A ZINCLESS FINGERTITL 3 MOTIF REQUIRED FOR GLYCOSYLASE ACTIVITY.REF PROC.NATL.ACAD.SCI.USA V. 101 10284 2004REFN ISSN 0027-8424PMID 15232006DOI 10.1073/PNAS.0402051101 Variant Set Distributions Mapped Variants
General Structure Information 3ngo CNOT6L crystal structure of the human cnot6l nuclease domain in complex with poly(a) dna 2.2Å AUTH H.WANG,M.MORITA,X.YANG,T.SUZUKI,W.YANG,J.WANG,K.ITO,Q.WANG,AUTH 2 C.ZHAO,M.BARTLAM,T.YAMAMOTO,Z.RAOTITL CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAINTITL 2 REVEALS STRICT POLY(A) SUBSTRATE SPECIFICITY.REF EMBO J. 2010REFN ESSN 1460-2075PMID 20628353DOI 10.1038/EMBOJ.2010.152 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2lmd PROX1 minimal constraints solution nmr structure of prospero homeobox protein 1 from homo sapiens, northeast structural genomics consortium target hr4660b -1.0Å AUTH O.F.LANGE,P.ROSSI,N.G.SGOURAKIS,Y.SONG,H.W.LEE,J.M.ARAMINI,AUTH 2 A.ERTEKIN,R.XIAO,T.B.ACTON,G.T.MONTELIONE,D.BAKERTITL DETERMINATION OF SOLUTION STRUCTURES OF PROTEINS UP TO 40TITL 2 KDA USING CS-ROSETTA WITH SPARSE NMR DATA FROM DEUTERATEDTITL 3 SAMPLES.REF PROC.NATL.ACAD.SCI.USA V. 109 10873 2012REFN […]