Assessment of Structural Intolerance and Durability
General Structure Information 2ene ZNF347 solution structure of the c2h2 type zinc finger (region 592- 624) of human zinc finger protein 347 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 592-624) OF HUMAN ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3g65 RAD9A crystal structure of the human rad9-rad1-hus1 dna damage checkpoint complex 2.9Å AUTH A.S.DORE,M.L.KILKENNY,N.J.RZECHORZEK,L.H.PEARLTITL CRYSTAL STRUCTURE OF THE RAD9-RAD1-HUS1 DNA DAMAGETITL 2 CHECKPOINT COMPLEX–IMPLICATIONS FOR CLAMP LOADING ANDTITL 3 REGULATION.REF MOL.CELL V. 34 735 2009REFN ISSN 1097-2765PMID 19446481DOI 10.1016/J.MOLCEL.2009.04.027 Variant Set Distributions Mapped Variants
General Structure Information 3oln UHRF2 crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf2 2.3Å AUTH J.R.WALKER,S.XUE,G.V.AVVAKUMOV,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE SET AND RING ASSOCIATED (SRA) DOMAIN OF HUMANTITL 2 UBIQUITIN-LIKE CONTAINING PHD AND RING FINGER DOMAINS 2TITL 3 (UHRF2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ccz MTR crystal structure of human 5-methyltetrahydrofolate- homocysteine methyltransferase, the homocysteine and folate binding domains 2.7Å AUTH M.VOLLMAR,W.KIYANI,T.KROJER,S.GOUBIN,N.BURGESS-BROWN,AUTH 2 F.VON DELFT,U.OPPERMANN,A.EDWARDS,C.ARROWSMITH,C.BOUNTRA,AUTH 3 W.W.YUETITL CRYSTAL STRUCTURE OF HUMAN 5-TITL 2 METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE, THETITL 3 HOMOCYSTEINE AND FOLATE BINDING DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2v66 NDEL1 crystal structure of the coiled-coil domain of ndel1 (a.a. 58 to 169)c 2.1Å AUTH U.DEREWENDA,C.TARRICONE,W.C.CHOI,D.R.COOPER,S.LUKASIK,AUTH 2 F.PERRINA,A.TRIPATHY,M.H.KIM,D.S.CAFISO,A.MUSACCHIO,AUTH 3 Z.S.DEREWENDATITL THE STRUCTURE OF THE COILED-COIL DOMAIN OF NDEL1 AND THETITL 2 BASIS OF ITS INTERACTION WITH LIS1, THE CAUSAL PROTEIN OFTITL 3 MILLER-DIEKER LISSENCEPHALY.REF STRUCTURE V. 15 1467 2007REFN ISSN 0969-2126PMID […]
General Structure Information 2h58 KIFC3 crystal structure of the kifc3 motor domain in complex with adp 1.85Å AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE KIFC3 MOTOR DOMAIN INTITL 2 COMPLEX WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3eay SENP7 crystal structure of the human senp7 catalytic domain 2.4Å AUTH C.D.LIMA,D.REVERTERTITL STRUCTURE OF THE HUMAN SENP7 CATALYTIC DOMAIN ANDTITL 2 POLY-SUMO DECONJUGATION ACTIVITIES FOR SENP6 ANDTITL 3 SENP7.REF J.BIOL.CHEM. V. 283 32045 2008REFN ISSN 0021-9258PMID 18799455DOI 10.1074/JBC.M805655200 Variant Set Distributions Mapped Variants
General Structure Information 3ohv BACH2 crystal structure of the human bach2 poz domain, form ii 2.2Å AUTH G.O.ROSBROOK,M.A.STEAD,S.B.CARR,S.C.WRIGHTTITL THE STRUCTURE OF THE BACH2 POZ-DOMAIN DIMER REVEALS ANTITL 2 INTERSUBUNIT DISULFIDE BOND.REF ACTA CRYSTALLOGR.,SECT.D V. 68 26 2012REFN ISSN 0907-4449PMID 22194330DOI 10.1107/S0907444911048335 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2yy0 MYCBP crystal structure of ms0802, c-myc-1 binding protein domain from homo sapiens 2.4Å AUTH Y.XIE,H.WANG,IHSANAWATI,S.KISHISHITA,C.TAKEMOTO,AUTH 2 K.MURAYAMA,M.SHIROZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF C-MYC-1 BINDING PROTEINTITL 2 DOMAIN FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l9s PHF12 solution structure of pf1 sid1-msin3a pah2 complex -1.0Å AUTH G.S.KUMAR,T.XIE,Y.ZHANG,I.RADHAKRISHNANTITL SOLUTION STRUCTURE OF THE MSIN3A PAH2-PF1 SID1 COMPLEX: ATITL 2 MAD1/MXD1-LIKE INTERACTION DISRUPTED BY MRG15 IN THETITL 3 RPD3S/SIN3S COMPLEX.REF J.MOL.BIOL. V. 408 987 2011REFN ISSN 0022-2836PMID 21440557DOI 10.1016/J.JMB.2011.03.043 Variant Set Distributions Mapped Variants