Assessment of Structural Intolerance and Durability
General Structure Information 2dlk ZNF692 solution structure of the first and the second zf-c2h2 domains of zinc finger protein 692 -1.0Å AUTH H.P.ZHANG,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND THE SECONDTITL 2 ZF-C2H2 DOMAINS OF ZINC FINGER PROTEIN 692REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2db8 TRIM9 solution structures of the fn3 domain of human tripartite motif protein 9 -1.0Å AUTH M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 TRIPARTITE MOTIF PROTEIN 9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3iv1 TSG101 coiled-coil domain of tumor susceptibility gene 101 2.5Å AUTH D.NECULAI,G.V.AVVAKUMOV,A.K.WERNIMONT,S.XUE,AUTH 2 J.R.WALKER,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL COILED-COIL DOMAIN OF HUMAN TSG101REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z5e PSMG3 crystal structure of proteasome assembling chaperone 3 2.0Å AUTH H.YASHIRODA,T.MIZUSHIMA,K.OKAMOTO,T.KAMEYAMA,AUTH 2 H.HAYASHI,T.KISHIMOTO,S.NIWA,M.KASAHARA,E.KURIMOTO,AUTH 3 E.SAKATA,K.TAKAGI,A.SUZUKI,Y.HIRANO,S.MURATA,AUTH 4 K.KATO,T.YAMANE,K.TANAKATITL CRYSTAL STRUCTURE OF A CHAPERONE COMPLEX THATTITL 2 CONTRIBUTES TO THE ASSEMBLY OF YEAST 20STITL 3 PROTEASOMESREF NAT.STRUCT.MOL.BIOL. V. 15 228 2008REFN ISSN 1545-9993PMID 18278057DOI 10.1038/NSMB.1386 Variant Set Distributions Mapped Variants
General Structure Information 2din CDC5L solution structure of the myb_dna-binding domain of human cell division cycle 5-like protein -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE MYB_DNA-BINDING DOMAINTITL 2 OF HUMAN CELL DIVISION CYCLE 5-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3egi TGS1 methyltransferase domain of human trimethylguanosine synthase tgs1 bound to m7gpppa (inactive form) 2.21Å AUTH T.MONECKE,A.DICKMANNS,A.STRASSER,R.FICNERTITL STRUCTURE ANALYSIS OF THE CONSERVED METHYLTRANSFERASE DOMAINTITL 2 OF HUMAN TRIMETHYLGUANOSINE SYNTHASE TGS1.REF ACTA CRYSTALLOGR.,SECT.D V. 65 332 2009REFN ISSN 0907-4449PMID 19307714DOI 10.1107/S0907444909003102 Variant Set Distributions Mapped Variants
General Structure Information 2j4e ITPA the itp complex of human inosine triphosphatase 2.8Å AUTH P.STENMARK,P.KURSULA,S.FLODIN,S.GRASLUND,R.LANDRY,AUTH 2 P.NORDLUND,H.SCHULERTITL CRYSTAL STRUCTURE OF HUMAN INOSINE TRIPHOSPHATASE:TITL 2 SUBSTRATE BINDING AND IMPLICATION OF THE INOSINETITL 3 TRIPHOSPHATASE DEFICIENCY MUTATION P32T.REF J.BIOL.CHEM. V. 282 3182 2007REFN ISSN 0021-9258PMID 17138556DOI 10.1074/JBC.M609838200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3ow8 WDR61 crystal structure of the wd repeat-containing protein 61 2.3Å AUTH C.XU,J.MINTITL STRUCTURE AND FUNCTION OF WD40 DOMAIN PROTEINS.REF PROTEIN CELL V. 2 202 2011REFN ISSN 1674-800XPMID 21468892DOI 10.1007/S13238-011-1018-1 Variant Set Distributions Mapped Variants
General Structure Information 4giw RUSC1 crystal structure of the run domain of human nesca 2.0Å AUTH Q.SUN,C.HAN,L.LIU,Y.WANG,H.DENG,L.BAI,T.JIANGTITL CRYSTAL STRUCTURE AND FUNCTIONAL IMPLICATION OF THE RUNTITL 2 DOMAIN OF HUMAN NESCAREF PROTEIN CELL V. 3 609 2012REFN ISSN 1674-800XPMID 22821014DOI 10.1007/S13238-012-2052-3 Variant Set Distributions Mapped Variants
General Structure Information 1y97 TREX2 the human trex2 3 exonuclease structure suggests a mechanism for efficient non-processive dna catalysis 2.5Å AUTH F.W.PERRINO,S.HARVEY,S.MCMILLIN,T.HOLLISTITL THE HUMAN TREX2 3 -> 5-EXONUCLEASE STRUCTURETITL 2 SUGGESTS A MECHANISM FOR EFFICIENT NONPROCESSIVETITL 3 DNA CATALYSIS.REF J.BIOL.CHEM. V. 280 15212 2005REFN ISSN 0021-9258PMID 15661738DOI 10.1074/JBC.M500108200 Variant Set Distributions Ripley’s K Analysis Plots […]