3EGI.A | TGS1

General Structure Information

PDB ID 3egi
HGNC Gene Label(s) TGS1
Structure Name methyltransferase domain of human trimethylguanosine synthase tgs1 bound to m7gpppa (inactive form)
Resolution 2.21Å
Reference AUTH T.MONECKE,A.DICKMANNS,A.STRASSER,R.FICNERTITL STRUCTURE ANALYSIS OF THE CONSERVED METHYLTRANSFERASE DOMAINTITL 2 OF HUMAN TRIMETHYLGUANOSINE SYNTHASE TGS1.REF ACTA CRYSTALLOGR.,SECT.D V. 65 332 2009REFN ISSN 0907-4449PMID 19307714DOI 10.1107/S0907444909003102

Variant Set Distributions

ExAC Variants

Number Of Residues 188
Number Of SNVs 51
Number Of Permutations 5868
Optimal Distance Threshold 6.0
K Statistic 0.034
p-value 0.034

Mapped Variants

[+] ExAC Missense Variants