Assessment of Structural Intolerance and Durability
General Structure Information 2k3w VPS4A nmr structure of vps4a-mit-chmp6 -1.0Å AUTH C.KIEFFER,J.J.SKALICKY,E.MORITA,I.DE DOMENICO,AUTH 2 D.M.WARD,J.KAPLAN,W.I.SUNDQUISTTITL TWO DISTINCT MODES OF ESCRT-III RECOGNITION ARETITL 2 REQUIRED FOR VPS4 FUNCTIONS IN LYSOSOMAL PROTEINTITL 3 TARGETING AND HIV-1 BUDDINGREF DEV.CELL V. 15 62 2008REFN ISSN 1534-5807PMID 18606141DOI 10.1016/J.DEVCEL.2008.05.014 Variant Set Distributions Mapped Variants
General Structure Information 3mao MSRB1 crystal structure of human methionine-r-sulfoxide reductase b1 (msrb1) 1.42Å AUTH A.CHAIKUAD,N.SHAFQAT,W.W.YUE,P.SAVITSKY,T.KROJER,AUTH 2 E.UGOCHUKWU,J.R.C.MUNIZ,A.C.W.PIKE,F.VON DELFT,AUTH 3 C.H ARROWSMITH,A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,AUTH 4 U.OPPERMANN,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN METHIONINE-R-SULFOXIDETITL 2 REDUCTASE B1 (MSRB1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3gqc REV1 structure of human rev1-dna-dntp ternary complex 2.5Å AUTH M.K.SWAN,R.E.JOHNSON,L.PRAKASH,S.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF THE HUMAN REV1-DNA-DNTP TERNARY COMPLEX.REF J.MOL.BIOL. V. 390 699 2009REFN ISSN 0022-2836PMID 19464298DOI 10.1016/J.JMB.2009.05.026 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2edp SHROOM4 solution structure of the pdz domain from human shroom family member 4 -1.0Å AUTH H.ENDO,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 SHROOM FAMILY MEMBER 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3o10 SACS crystal structure of the hepn domain from human sacsin 1.9Å AUTH G.KOZLOV,A.Y.DENISOV,M.GIRARD,M.J.DICAIRE,J.HAMLIN,AUTH 2 P.S.MCPHERSON,B.BRAIS,K.GEHRINGTITL STRUCTURAL BASIS OF DEFECTS IN THE SACSIN HEPN DOMAINTITL 2 RESPONSIBLE FOR AUTOSOMAL RECESSIVE SPASTIC ATAXIA OFTITL 3 CHARLEVOIX-SAGUENAY (ARSACS).REF J.BIOL.CHEM. V. 286 20407 2011REFN ISSN 0021-9258PMID 21507954DOI 10.1074/JBC.M111.232884 Variant Set Distributions Mapped Variants
General Structure Information 1uhp PDZRN3 solution structure of rsgi ruh-005, a pdz domain in human cdna, kiaa1095 -1.0Å AUTH T.HAMADA,Y.MUTO,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-005, A PDZ DOMAINTITL 2 IN HUMAN CDNA, KIAA1095REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3haj PACSIN2 crystal structure of human pacsin2 f-bar domain (p212121 lattice) 2.78Å AUTH Q.WANG,M.V.NAVARRO,G.PENG,E.MOLINELLI,S.LIN GOH,AUTH 2 B.L.JUDSON,K.R.RAJASHANKAR,H.SONDERMANNTITL MOLECULAR MECHANISM OF MEMBRANE CONSTRICTION ANDTITL 2 TUBULATION MEDIATED BY THE F-BAR PROTEINTITL 3 PACSIN/SYNDAPIN.REF PROC.NATL.ACAD.SCI.USA V. 106 12700 2009REFN ISSN 0027-8424PMID 19549836DOI 10.1073/PNAS.0902974106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2i7t CPSF3 structure of human cpsf-73 2.1Å AUTH C.R.MANDEL,S.KANEKO,H.ZHANG,D.GEBAUER,V.VETHANTHAM,AUTH 2 J.L.MANLEY,L.TONGTITL POLYADENYLATION FACTOR CPSF-73 IS THE PRE-MRNATITL 2 3-END-PROCESSING ENDONUCLEASE.REF NATURE V. 444 953 2006REFN ISSN 0028-0836PMID 17128255DOI 10.1038/NATURE05363 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2r13 CISD1 crystal structure of human mitoneet reveals a novel [2fe- 2s] cluster coordination 1.8Å AUTH X.HOU,R.LIU,S.ROSS,E.J.SMART,H.ZHU,W.GONGTITL CRYSTALLOGRAPHIC STUDIES OF HUMAN MITONEETREF J.BIOL.CHEM. V. 282 33242 2007REFN ISSN 0021-9258PMID 17905743DOI 10.1074/JBC.C700172200 Variant Set Distributions Mapped Variants
General Structure Information 3jyh DPP7 human dipeptidyl peptidase dpp7 2.19Å AUTH E.DOBROVETSKY,A.DONG,A.SEITOVA,L.CROMBETT,S.PAGANON,AUTH 2 D.COSSAR,A.M.EDWARDS,C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,AUTH 3 A.HASSEL,L.SHEWCHUK,A.BOCHKAREVTITL HUMAN DIPEPTIDYL PEPTIDASE DPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants