Assessment of Structural Intolerance and Durability
General Structure Information 2ee1 CHD4 solution structures of the chromo domain of human chromodomain helicase-dna-binding protein 4 -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE CHROMO DOMAIN OF HUMANTITL 2 CHROMODOMAIN HELICASE-DNA-BINDING PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lb6 IL13RA2 the structure of il-13 in complex with il-13ralpha2 3.05Å AUTH P.J.LUPARDUS,M.E.BIRNBAUM,K.C.GARCIATITL MOLECULAR BASIS FOR SHARED CYTOKINE RECOGNITION REVEALED INTITL 2 THE STRUCTURE OF AN UNUSUALLY HIGH AFFINITY COMPLEX BETWEENTITL 3 IL-13 AND IL-13RALPHA2.REF STRUCTURE V. 18 332 2010REFN ISSN 0969-2126PMID 20223216DOI 10.1016/J.STR.2010.01.003 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4bkx HDAC1 the structure of hdac1 in complex with the dimeric elm2-sant domain of mta1 from the nurd complex 3.0Å AUTH C.J.MILLARD,P.J.WATSON,I.CELARDO,Y.GORDIYENKO,S.M.COWLEY,AUTH 2 C.V.ROBINSON,L.FAIRALL,J.W.R.SCHWABETITL CLASS I HDACS SHARE A COMMON MECHANISM OF REGULATION BYTITL 2 INOSITOL PHOSPHATES.REF MOL.CELL V. 51 57 2013REFN ISSN 1097-2765PMID 23791785DOI 10.1016/J.MOLCEL.2013.05.020 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3h8m EPHA7 sam domain of human ephrin type-a receptor 7 (epha7) 2.1Å AUTH J.R.WALKER,L.YERMEKBAYEVA,C.BUTLER-COLE,C.BOUNTRA,AUTH 2 J.WEIGELT,C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL SAM DOMAIN OF HUMAN EPHRIN TYPE-A RECEPTOR 7TITL 2 (EPHA7)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4fg8 CAMK1 crystal structure of human calcium/calmodulin-dependent protein kinase i 1-315 in complex with atp 2.2Å AUTH M.ZHA,C.ZHONG,Y.OU,L.HAN,J.WANG,J.DINGTITL CRYSTAL STRUCTURES OF HUMAN CAMKIALPHA REVEAL INSIGHTS INTOTITL 2 THE REGULATION MECHANISM OF CAMKI.REF PLOS ONE V. 7 44828 2012REFN ESSN 1932-6203PMID 23028635DOI 10.1371/JOURNAL.PONE.0044828 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2lcx ERBB4 spatial structure of the erbb4 dimeric tm domain -1.0Å AUTH E.V.BOCHAROV,K.S.MINEEV,M.V.GONCHARUK,A.S.ARSENIEVTITL STRUCTURAL AND THERMODYNAMIC INSIGHT INTO THE PROCESS OFTITL 2 WEAK DIMERIZATION OF THE ERBB4 TRANSMEMBRANE DOMAIN BYTITL 3 SOLUTION NMR.REF BIOCHIM.BIOPHYS.ACTA V.1818 2158 2012REFN ISSN 0006-3002PMID 22579757DOI 10.1016/J.BBAMEM.2012.05.001 Variant Set Distributions Mapped Variants
General Structure Information 3orh GAMT human guanidinoacetate n-methyltransferase with sah 1.86Å AUTH H.WU,A.DONG,H.ZENG,P.LOPPNAU,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN GUANIDINOACETATETITL 2 N-METHYLTRANSFERASE WITH SAHREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dlm SETDB1 crystal structure of tudor domain of human histone-lysine n- methyltransferase setdb1 1.77Å AUTH L.DOMBROVSKI,M.F.AMAYA,P.LOPPNAU,A.BOCHKAREV,J.MIN,AUTH 2 H.WUTITL THE CRYSTAL STRUCTURE OF TUDOR DOMAIN OF HUMANTITL 2 HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2oo1 BRD3 crystal structure of the bromo domain 2 of human bromodomain containing protein 3 (brd3) 1.7Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1v05 FLNC dimerization of human filamin c: crystal structure of the domain 24 1.43Å AUTH R.PUDAS,T.-R.KIEMA,P.J.G.BUTLER,M.STEWART,J.YLANNETITL STRUCTURAL BASIS FOR VERTEBRATE FILAMINTITL 2 DIMERIZATIONREF STRUCTURE V. 13 111 2005REFN ISSN 0969-2126PMID 15642266DOI 10.1016/J.STR.2004.10.014 Variant Set Distributions Mapped Variants