3DLM.A | SETDB1

PDB ID	3dlm
HGNC Gene Label(s)	SETDB1
Structure Name	crystal structure of tudor domain of human histone-lysine n- methyltransferase setdb1
Resolution	1.77Å
Reference	AUTH L.DOMBROVSKI,M.F.AMAYA,P.LOPPNAU,A.BOCHKAREV,J.MIN,AUTH 2 H.WUTITL THE CRYSTAL STRUCTURE OF TUDOR DOMAIN OF HUMANTITL 2 HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1.REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
1:150915099	rs371182642	R>Q	A:14	(45.00, 69.63, 5.90)
1:150915120		T>I	A:21	(33.74, 55.00, 0.45)
1:150915356		F>L	A:45	(42.67, 62.16, 0.33)
1:150915361	rs2271075	N>S	A:47	(46.40, 57.78, 2.74)
1:150915385		G>E	A:55	(32.47, 71.55, -3.38)
1:150915406		Y>C	A:62	(36.03, 74.94, 10.31)
1:150915415		P>H	A:65	(29.78, 78.88, 14.55)
1:150915450	COSM1667915 COSM1667916 COSM1667917	A>T	A:77	(29.17, 63.91, 10.82)
1:150915453		K>E	A:78	(31.18, 61.45, 14.84)
1:150915513		V>I	A:98	(15.17, 72.52, 25.95)
1:150916443	rs201070262	S>L	A:119	(32.34, 68.64, 18.39)
1:150916445		E>K	A:120	(30.41, 65.31, 16.81)
1:150916463		R>W	A:126	(31.97, 76.08, -1.56)
1:150916464		R>Q	A:126	(31.97, 76.08, -1.56)
1:150916466	rs587594550	P>A	A:127	(26.85, 74.35, -0.41)
1:150917403		T>S	A:131	(21.25, 71.54, 0.55)
1:150917432		R>C	A:141	(16.57, 63.68, -3.25)
1:150917433	rs200241875 COSM1333887 COSM1333888	R>H	A:141	(16.57, 63.68, -3.25)
1:150917451		Y>C	A:147	(12.38, 68.35, 8.12)
1:150917469	rs377370666	N>S	A:153	(6.25, 71.95, 10.26)
1:150917511		T>S	A:167	(8.44, 49.18, 11.78)
1:150917526		T>M	A:172	(8.15, 44.55, 4.87)
1:150917579		F>L	A:190	(12.62, 45.50, 14.56)
1:150917582		L>M	A:191	(9.60, 41.84, 18.48)
1:150919402		R>Q	A:205	(11.31, 52.79, 8.78)

3DLM.A | SETDB1.