General Structure Information
| PDB ID | 3lb6 |
| HGNC Gene Label(s) | IL13RA2 |
| Structure Name | the structure of il-13 in complex with il-13ralpha2 |
| Resolution | 3.05Å |
| Reference | AUTH P.J.LUPARDUS,M.E.BIRNBAUM,K.C.GARCIATITL MOLECULAR BASIS FOR SHARED CYTOKINE RECOGNITION REVEALED INTITL 2 THE STRUCTURE OF AN UNUSUALLY HIGH AFFINITY COMPLEX BETWEENTITL 3 IL-13 AND IL-13RALPHA2.REF STRUCTURE V. 18 332 2010REFN ISSN 0969-2126PMID 20223216DOI 10.1016/J.STR.2010.01.003 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 250 |
| Number Of SNVs | 31 |
| Number Of Permutations | 23402 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.028 |
| p-value | 0.279 |
COSMIC
| Number Of Residues | 250 |
| Number Of SNVs | 5 |
| Number Of Permutations | 675 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.2 |
| p-value | 0.617 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 31 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.574 |
| p-value | 0.41 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
