Assessment of Structural Intolerance and Durability
General Structure Information 2e7c MYBPC2 solution structure of the 6th ig-like domain from human myosin-binding protein c, fast-type -1.0Å AUTH X.R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 6TH IG-LIKE DOMAIN FROMTITL 2 HUMAN MYOSIN-BINDING PROTEIN C, FAST-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uap PCOLCE nmr structure of the ntr domain from human pcolce1 -1.0Å AUTH E.LIEPINSH,L.BANYAI,G.PINTACUDA,M.TREXLER,L.PATTHY,AUTH 2 G.OTTINGTITL NMR STRUCTURE OF THE NETRIN-LIKE DOMAIN (NTR) OFTITL 2 HUMAN TYPE I PROCOLLAGEN C-PROTEINASE ENHANCERTITL 3 DEFINES STRUCTURAL CONSENSUS OF NTR DOMAINS ANDTITL 4 ASSESSES POTENTIAL PROTEINASE INHIBITORY ACTIVITYTITL 5 AND LIGAND BINDING.REF J.BIOL.CHEM. V. 278 […]
General Structure Information 1i16 IL16 structure of interleukin 16: implications for function, nmr, 20 structures -1.0Å AUTH P.MUHLHAHN,M.ZWECKSTETTER,J.GEORGESCU,C.CIOSTO,AUTH 2 C.RENNER,M.LANZENDORFER,K.LANG,D.AMBROSIUS,M.BAIER,AUTH 3 R.KURTH,T.A.HOLAKTITL STRUCTURE OF INTERLEUKIN 16 RESEMBLES A PDZ DOMAINTITL 2 WITH AN OCCLUDED PEPTIDE BINDING SITE.REF NAT.STRUCT.BIOL. V. 5 682 1998REFN ISSN 1072-8368PMID 9699630DOI 10.1038/1376 Variant Set Distributions Mapped Variants
General Structure Information 1em2 STARD3 star-related lipid transport domain of mln64 2.2Å AUTH Y.TSUJISHITA,J.H.HURLEYTITL STRUCTURE AND LIPID TRANSPORT MECHANISM OF A STAR-RELATEDTITL 2 DOMAIN.REF NAT.STRUCT.BIOL. V. 7 408 2000REFN ISSN 1072-8368PMID 10802740DOI 10.1038/75192 Variant Set Distributions Mapped Variants
General Structure Information 3ch4 PMVK the crystal structure of human phosphomavelonate kinase at 1.8 a resolution 1.76Å AUTH Q.CHANG,X.-X.YAN,S.-Y.GU,J.-F.LIU,D.-C.LIANGTITL CRYSTAL STRUCTURE OF HUMAN PHOSPHOMAVELONATETITL 2 KINASE AT 1.8 A RESOLUTIONREF PROTEINS V. 73 254 2008REFN ISSN 0887-3585PMID 18618710DOI 10.1002/PROT.22151 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2he2 DLG2 crystal structure of the 3rd pdz domain of human discs large homologue 2, dlg2 1.5Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,AUTH 2 C.PHILLIPS,C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINEDTITL 2 WITH THE HELP OF SELF-BINDING C-TERMINALTITL 3 EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped […]
General Structure Information 2qy7 CLINT1 crystal structure of human epsinr enth domain 2.0Å AUTH S.E.MILLER,B.M.COLLINS,A.J.MCCOY,M.S.ROBINSON,AUTH 2 D.J.OWENTITL A SNARE-ADAPTOR INTERACTION IS A NEW MODE OF CARGOTITL 2 RECOGNITION IN CLATHRIN-COATED VESICLES.REF NATURE V. 450 570 2007REFN ISSN 0028-0836PMID 18033301DOI 10.1038/NATURE06353 Variant Set Distributions Mapped Variants
General Structure Information 4hxi CUL3 crystal structure of klhl3/cul3 complex 3.51Å AUTH A.X.JI,G.G.PRIVETITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF KLHL3/CUL3TITL 2 COMPLEX AND IMPLICATIONS OF FHHT MUTATIONS IN CUL3 BINDINGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2me6 GBX1 nmr structure of the homeodomain transcription factor gbx1 from homo sapiens in complex with the dna sequence cgactaattagtcg -1.0Å AUTH A.PROUDFOOT,K.WUTHRICH,P.SERRANO,M.GERALTTITL NMR STRUCTURE OF THE HOMEODOMAIN TRANSCRIPTION FACTOR GBX1TITL 2 FROM HOMO SAPIENS IN COMPLEX WITH THE DNA SEQUENCETITL 3 CGACTAATTAGTCGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1wgr GRB7 solution structure of the ra domain of human grb7 protein -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN OF HUMAN GRB7TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants