3SE2.A | PARP14

General Structure Information 3se2 PARP14 human poly(adp-ribose) polymerase 14 (parp14/artd8) – catalytic domain in complex with 6(5h)-phenanthridinone 2.3Å AUTH E.WAHLBERG,T.KARLBERG,E.KOUZNETSOVA,N.MARKOVA,A.MACCHIARULO,AUTH 2 A.G.THORSELL,E.POL,A.FROSTELL,T.EKBLAD,D.ONCU,B.KULL,AUTH 3 G.M.ROBERTSON,R.PELLICCIARI,H.SCHULER,J.WEIGELTTITL FAMILY-WIDE CHEMICAL PROFILING AND STRUCTURAL ANALYSIS OFTITL 2 PARP AND TANKYRASE INHIBITORS.REF NAT.BIOTECHNOL. V. 30 283 2012REFN ISSN 1087-0156PMID 22343925DOI 10.1038/NBT.2121 Variant Set Distributions Mapped Variants

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1WFO.A | SDK2

General Structure Information 1wfo SDK2 the eighth fn3 domain of human sidekick-2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL THE EIGHTH FN3 DOMAIN OF HUMAN SIDEKICK-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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4BOU.A | OTUD3

General Structure Information 4bou OTUD3 structure of otud3 otu domain 1.55Å AUTH T.E.T.MEVISSEN,M.K.HOSPENTHAL,P.P.GEURINK,P.R.ELLIOTT,AUTH 2 M.AKUTSU,N.ARNAUDO,R.EKKEBUS,Y.KULATHU,T.WAUER,F.EL OUALID,AUTH 3 S.M.V.FREUND,H.OVAA,D.KOMANDERTITL OTU DEUBIQUITINASES REVEAL MECHANISMS OF LINKAGETITL 2 SPECIFICITY AND ENABLE UBIQUITIN CHAIN RESTRICTIONTITL 3 ANALYSIS.REF CELL(CAMBRIDGE,MASS.) V. 154 169 2013REFN ISSN 0092-8674PMID 23827681DOI 10.1016/J.CELL.2013.05.046 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]

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2DMI.A | TSHZ3

General Structure Information 2dmi TSHZ3 solution structure of the first and the second zf-c2h2 like domains of human teashirt homolog 3 -1.0Å AUTH H.ENDO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND THE SECONDTITL 2 ZF-C2H2 LIKE DOMAINS OF HUMAN TEASHIRT HOMOLOG 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]

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3L4H.A | HECW1

General Structure Information 3l4h HECW1 helical box domain and second ww domain of the human e3 ubiquitin- protein ligase hecw1 1.8Å AUTH J.R.WALKER,L.QIU,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL THE TANDEM HELICAL BOX AND SECOND WW DOMAINS OF HUMAN HECW1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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4CRS.A | PKN2

General Structure Information 4crs PKN2 human protein kinase n2 (pkn2, prkcl2) in complex with atpgammas 2.75Å AUTH S.MATHEA,S.KNAPPTITL STRUCTURE OF PKN2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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2XST.A | LCN15

General Structure Information 2xst LCN15 crystal structure of the human lipocalin 15 1.63Å AUTH J.R.C.MUNIZ,C.GILEADI,W.W.YUE,T.KROJER,E.UGOCHUKWU,AUTH 2 C.PHILLIPS,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 3 C.BOUNTRA,K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE HUMAN LIPOCALIN 15REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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2KDD.A | CDCA8

General Structure Information 2kdd CDCA8 solution structure of the conserved c-terminal dimerization domain of borealin -1.0Å AUTH E.BOURHIS,A.LINGEL,Q.PHUNG,W.J.FAIRBROTHER,AUTH 2 A.G.COCHRANTITL PHOSPHORYLATION OF A BOREALIN DIMERIZATION DOMAINTITL 2 IS REQUIRED FOR PROPER CHROMOSOME SEGREGATION.REF BIOCHEMISTRY V. 48 6783 2009REFN ISSN 0006-2960PMID 19530738DOI 10.1021/BI900530V Variant Set Distributions Mapped Variants

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2Y96.A | DUPD1

General Structure Information 2y96 DUPD1 structure of human dual-specificity phosphatase 27 2.38Å AUTH G.T.LOUNTOS,J.E.TROPEA,D.S.WAUGHTITL STRUCTURE OF HUMAN DUAL-SPECIFICITY PHOSPHATASETITL 2 AT 2.38A RESOLUTIONREF ACTA CRYSTALLOGR.,SECT.D V. 67 471 2011REFN ISSN 0907-4449PMID 21543850DOI 10.1107/S090744491100970X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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2LZ1.A | NFE2L2

General Structure Information 2lz1 NFE2L2 solution nmr structure of the dna-binding domain of human nf-e2- related factor 2, northeast structural genomics consortium (nesg) target hr3520o -1.0Å AUTH A.ELETSKY,S.V.S.R.K.PULAVARTI,D.LEE,E.KOHAN,H.JANJUA,R.XIAO,AUTH 2 T.B.ACTON,J.K.EVERETT,G.T.MONTELIONE,T.SZYPERSKITITL SOLUTION NMR STRUCTURE OF THE DNA-BINDING DOMAIN OF HUMANTITL 2 NF-E2-RELATED FACTOR 2, NORTHEAST STRUCTURAL GENOMICSTITL 3 CONSORTIUM (NESG) TARGET HR3520OREF TO BE PUBLISHEDREFN Variant […]

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