General Structure Information
| PDB ID | 3l4h |
| HGNC Gene Label(s) | HECW1 |
| Structure Name | helical box domain and second ww domain of the human e3 ubiquitin- protein ligase hecw1 |
| Resolution | 1.8Å |
| Reference | AUTH J.R.WALKER,L.QIU,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL THE TANDEM HELICAL BOX AND SECOND WW DOMAINS OF HUMAN HECW1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 107 |
| Number Of SNVs | 26 |
| Number Of Permutations | 1715 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.12 |
| p-value | 0.035 |
COSMIC
| Number Of Residues | 107 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
