General Structure Information
| PDB ID | 2y96 |
| HGNC Gene Label(s) | DUPD1 |
| Structure Name | structure of human dual-specificity phosphatase 27 |
| Resolution | 2.38Å |
| Reference | AUTH G.T.LOUNTOS,J.E.TROPEA,D.S.WAUGHTITL STRUCTURE OF HUMAN DUAL-SPECIFICITY PHOSPHATASETITL 2 AT 2.38A RESOLUTIONREF ACTA CRYSTALLOGR.,SECT.D V. 67 471 2011REFN ISSN 0907-4449PMID 21543850DOI 10.1107/S090744491100970X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 175 |
| Number Of SNVs | 56 |
| Number Of Permutations | 9512 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.049 |
| p-value | 0.961 |
COSMIC
| Number Of Residues | 175 |
| Number Of SNVs | 6 |
| Number Of Permutations | 549 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.533 |
| p-value | 0.656 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 56 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.457 |
| p-value | 0.373 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
