Assessment of Structural Intolerance and Durability
General Structure Information 4lla LILRB2 crystal structure of d3d4 domain of the lilrb2 molecule 2.5Å AUTH G.NAM,Y.SHI,M.RYU,Q.WANG,H.SONG,J.LIU,J.YAN,J.QI,G.F.GAOTITL CRYSTAL STRUCTURES OF THE TWO MEMBRANE-PROXIMAL IG-LIKETITL 2 DOMAINS (D3D4) OF LILRB1/B2: ALTERNATIVE MODELS FOR THEIRTITL 3 INVOLVEMENT IN PEPTIDE-HLA BINDINGREF PROTEIN CELL V. 4 761 2013REFN ISSN 1674-800XPMID 23955630DOI 10.1007/S13238-013-3908-X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4ll9 LILRB1 crystal structure of d3d4 domain of the lilrb1 molecule 2.69Å AUTH G.NAM,Y.SHI,M.RYU,Q.WANG,H.SONG,J.LIU,J.YAN,J.QI,G.F.GAOTITL CRYSTAL STRUCTURES OF THE TWO MEMBRANE-PROXIMAL IG-LIKETITL 2 DOMAINS (D3D4) OF LILRB1/B2: ALTERNATIVE MODELS FOR THEIRTITL 3 INVOLVEMENT IN PEPTIDE-HLA BINDINGREF PROTEIN CELL V. 4 761 2013REFN ISSN 1674-800XPMID 23955630DOI 10.1007/S13238-013-3908-X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3t30 NPM2 human nucleoplasmin (npm2): a histone chaperone in oocytes and early embryos 1.9Å AUTH O.PLATONOVA,I.V.AKEY,J.F.HEAD,C.W.AKEYTITL CRYSTAL STRUCTURE AND FUNCTION OF HUMAN NUCLEOPLASMINTITL 2 (NPM2): A HISTONE CHAPERONE IN OOCYTES AND EMBRYOS.REF BIOCHEMISTRY V. 50 8078 2011REFN ISSN 0006-2960PMID 21863821DOI 10.1021/BI2006652 Variant Set Distributions Mapped Variants
General Structure Information 2jc6 CAMK1D crystal structure of human calmodulin-dependent protein kinase 1d 2.3Å AUTH J.E.DEBRECZENI,P.RELLOS,O.FEDOROV,F.H.NIESEN,C.BHATIA,AUTH 2 L.SHRESTHA,E.SALAH,C.SMEE,S.COLEBROOK,G.BERRIDGE,O.GILEADI,AUTH 3 G.BUNKOCZI,E.UGOCHUKWU,A.C.W.PIKE,F.VON DELFT,S.KNAPP,AUTH 4 M.SUNDSTROM,J.WEIGELT,C.H.ARROWSMITH,A.EDWARDSTITL CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEINTITL 2 KINASE 1DREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4k6j WAPAL human cohesin inhibitor wapl 2.62Å AUTH Z.OUYANG,G.ZHENG,J.SONG,D.M.BOREK,Z.OTWINOWSKI,AUTH 2 C.A.BRAUTIGAM,D.R.TOMCHICK,S.RANKIN,H.YUTITL STRUCTURE OF THE HUMAN COHESIN INHIBITOR WAPL.REF PROC.NATL.ACAD.SCI.USA V. 110 11355 2013REFN ISSN 0027-8424PMID 23776203DOI 10.1073/PNAS.1304594110 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1ugn LILRB1 crystal structure of lir1.02, one of the alleles of lir1 1.8Å AUTH K.KUROKI,N.TSUCHIYA,M.SHIROISHI,L.RASUBALA,AUTH 2 Y.YAMASHITA,K.MATSUTA,T.FUKAZAWA,M.KUSAOI,AUTH 3 Y.MURAKAMI,M.TAKIGUCHI,T.JUJI,H.HASHIMOTO,D.KOHDA,AUTH 4 K.MAENAKA,K.TOKUNAGATITL EXTENSIVE POLYMORPHISMS OF LILRB1 (ILT2, LIR1) ANDTITL 2 THEIR ASSOCIATION WITH HLA-DRB1 SHARED EPITOPETITL 3 NEGATIVE RHEUMATOID ARTHRITIS.REF HUM.MOL.GENET. V. 14 2469 2005REFN ISSN 0964-6906PMID 16014635DOI 10.1093/HMG/DDI247 Variant Set Distributions Ripley’s […]
General Structure Information 3g1n HUWE1 catalytic domain of the human e3 ubiquitin-protein ligase huwe1 2.6Å AUTH J.R.WALKER,L.QIU,Y.LI,T.DAVIS,W.TEMPEL,J.WEIGELT,AUTH 2 C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,AUTH 3 S.DHE-PAGANONTITL HECT DOMAIN OF HUMAN HUWE1/MULEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2db2 DHX30 solution structure of the double-stranded rna binding domain in kiaa0890 protein -1.0Å AUTH C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DOUBLE-STRANDED RNATITL 2 BINDING DOMAIN IN KIAA0890 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ew1 RAB30 crystal structure of rab30 in complex with a gtp analogue 2.0Å AUTH J.WANG,Y.SHEN,S.ISMAIL,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.W.PARKTITL CRYSTAL STRUCTURE OF RAB30 IN COMPLEX WITH A GTPTITL 2 ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3waa H2AFV the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Mapped Variants