General Structure Information
| PDB ID | 2jc6 |
| HGNC Gene Label(s) | CAMK1D |
| Structure Name | crystal structure of human calmodulin-dependent protein kinase 1d |
| Resolution | 2.3Å |
| Reference | AUTH J.E.DEBRECZENI,P.RELLOS,O.FEDOROV,F.H.NIESEN,C.BHATIA,AUTH 2 L.SHRESTHA,E.SALAH,C.SMEE,S.COLEBROOK,G.BERRIDGE,O.GILEADI,AUTH 3 G.BUNKOCZI,E.UGOCHUKWU,A.C.W.PIKE,F.VON DELFT,S.KNAPP,AUTH 4 M.SUNDSTROM,J.WEIGELT,C.H.ARROWSMITH,A.EDWARDSTITL CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEINTITL 2 KINASE 1DREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 278 |
| Number Of SNVs | 45 |
| Number Of Permutations | 7789 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.174 |
| p-value | 0.019 |
COSMIC
| Number Of Residues | 278 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1108 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.036 |
| p-value | 0.461 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.246 |
| p-value | 0.46 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
