Assessment of Structural Intolerance and Durability
General Structure Information 2d89 EHBP1 solution structure of the ch domain from human eh domain binding protein 1 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMAN EHTITL 2 DOMAIN BINDING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2k2m EPS8L1 structural basis of pxxdy motif recognition in sh3 binding -1.0Å AUTH O.AITIO,M.HELLMAN,T.KESTI,I.KLEINO,O.SAMUILOVA,AUTH 2 K.PAAKKONEN,H.TOSSAVAINEN,K.SAKSELA,P.PERMITITL STRUCTURAL BASIS OF PXXDY MOTIF RECOGNITION IN SH3TITL 2 BINDING.REF J.MOL.BIOL. V. 382 167 2008REFN ISSN 0022-2836PMID 18644376DOI 10.1016/J.JMB.2008.07.008 Variant Set Distributions Mapped Variants
General Structure Information 2jp2 SPRED2 solution structure and resonance assignment of the n- terminal evh1 domain from the human spred2 protein (sprouty-related protein with evh1 domain isoform 2) -1.0Å AUTH J.ZIMMERMANN,T.JARCHAU,U.WALTER,H.OSCHKINAT,AUTH 2 L.J.BALLTITL 1H, 13C AND 15N RESONANCE ASSIGNMENT OF THE HUMANTITL 2 SPRED2 EVH1 DOMAINREF J.BIOMOL.NMR V. 29 435 2004REFN ISSN 0925-2738PMID 15213456DOI 10.1023/B:JNMR.0000032526.17586.8C […]
General Structure Information 1h3i SETD7 crystal structure of the histone methyltransferase set7/9 2.1Å AUTH J.R.WILSON,C.JING,P.A.WALKER,S.R.MARTIN,S.A.HOWELL,AUTH 2 G.M.BLACKBURN,S.J.GAMBLIN,B.XIAOTITL CRYSTAL STRUCTURE AND FUNCTIONAL ANALYSIS OF THETITL 2 HISTONE METHYLTRANSFERASE SET7/9REF CELL(CAMBRIDGE,MASS.) V. 111 105 2002REFN ISSN 0092-8674PMID 12372304DOI 10.1016/S0092-8674(02)00964-9 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2l2l GATAD2A solution structure of the coiled-coil complex between mbd2 and p66alpha -1.0Å AUTH M.N.GNANAPRAGASAM,J.N.SCARSDALE,M.L.AMAYA,H.D.WEBB,AUTH 2 M.A.DESAI,N.M.WALAVALKAR,S.Z.WANG,S.ZU ZHU,G.D.GINDER,AUTH 3 D.C.WILLIAMSTITL P66ALPHA-MBD2 COILED-COIL INTERACTION AND RECRUITMENT OFTITL 2 MI-2 ARE CRITICAL FOR GLOBIN GENE SILENCING BY THE MBD2-NURDTITL 3 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 108 7487 2011REFN ISSN 0027-8424PMID 21490301DOI 10.1073/PNAS.1015341108 Variant Set Distributions Mapped […]
General Structure Information 3rc8 SUPV3L1 human mitochondrial helicase suv3 in complex with short rna fragment 2.9Å AUTH R.JEDRZEJCZAK,J.WANG,M.DAUTER,R.J.SZCZESNY,P.P.STEPIEN,AUTH 2 Z.DAUTERTITL HUMAN SUV3 PROTEIN REVEALS UNIQUE FEATURES AMONG SF2TITL 2 HELICASES.REF ACTA CRYSTALLOGR.,SECT.D V. 67 988 2011REFN ISSN 0907-4449PMID 22101826DOI 10.1107/S0907444911040248 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dgc IL22RA1 structure of il-22/il-22r1 2.5Å AUTH B.C.JONES,N.J.LOGSDON,M.R.WALTERTITL STRUCTURE OF IL-22 BOUND TO ITS HIGH-AFFINITY IL-22R1 CHAIN.REF STRUCTURE V. 16 1333 2008REFN ISSN 0969-2126PMID 18599299DOI 10.1016/J.STR.2008.06.005 Variant Set Distributions Mapped Variants
General Structure Information 4m7h FIBCD1 crystal structure of tetrameric fibrinogen-like recognition domain of fibcd1 2.0Å AUTH A.K.SHRIVE,J.B.MOELLER,I.BURNS,J.M.PATERSON,A.J.SHAW,AUTH 2 A.SCHLOSSER,G.L.SORENSEN,T.J.GREENHOUGH,U.HOLMSKOVTITL CRYSTAL STRUCTURE OF THE TETRAMERIC FIBRINOGEN-LIKETITL 2 RECOGNITION DOMAIN OF FIBRINOGEN C DOMAIN CONTAINING 1TITL 3 (FIBCD1) PROTEIN.REF J.BIOL.CHEM. V. 289 2880 2014REFN ISSN 0021-9258PMID 24293368DOI 10.1074/JBC.M113.520577 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1ueq MAGI2 solution structure of the first pdz domain of human atrophin-1 interacting protein 1 (kiaa0705 protein) -1.0Å AUTH C.ZHAO,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST PDZ DOMAIN OFTITL 2 HUMAN ATROPHIN-1 INTERACTING PROTEIN 1 (KIAA0705TITL 3 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2vsv RHPN2 crystal structure of the pdz domain of human rhophilin-2 1.82Å AUTH A.C.W.PIKE,G.KOCHAN,Z.SUN,N.SHAFQAT,E.S.PILKA,AUTH 2 A.ROOS,J.ELKINS,N.BURGESS-BROWN,J.W.MURRAY,AUTH 3 F.VON DELFT,M.WIKSTROM,A.EDWARDS,C.H.ARROWSMITH,AUTH 4 C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMANTITL 2 RHOPHILIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants