General Structure Information 1znq GAPDH crsytal structure of human liver gapdh 2.5Å AUTH S.A.ISMAIL,H.W.PARKTITL CRYSTAL STRUCTURE ANALYSIS OF HUMAN LIVER GAPDHREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2j3t TRAPPC6A the crystal structure of the bet3-trs33-bet5-trs23 complex. 2.4Å AUTH Y.KIM,S.RAUNSER,C.MUNGER,J.WAGNER,Y.SONG,M.CYGLER,T.WALZ,AUTH 2 B.OH,M.SACHERTITL THE ARCHITECTURE OF THE MULTISUBUNIT TRAPP I COMPLEXTITL 2 SUGGESTS A MODEL FOR VESICLE TETHERING.REF CELL(CAMBRIDGE,MASS.) V. 127 817 2006REFN ISSN 0092-8674PMID 17110339DOI 10.1016/J.CELL.2006.09.029 Variant Set Distributions Mapped Variants
General Structure Information 3s2k DKK1 structural basis of wnt signaling inhibition by dickkopf binding to lrp5/6. 2.8Å AUTH V.E.AHN,M.L.CHU,H.J.CHOI,D.TRAN,A.ABO,W.I.WEISTITL STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPFTITL 2 BINDING TO LRP5/6.REF DEV.CELL V. 21 862 2011REFN ISSN 1534-5807PMID 22000856DOI 10.1016/J.DEVCEL.2011.09.003 Variant Set Distributions Mapped Variants
General Structure Information 3s2k LRP6 structural basis of wnt signaling inhibition by dickkopf binding to lrp5/6. 2.8Å AUTH V.E.AHN,M.L.CHU,H.J.CHOI,D.TRAN,A.ABO,W.I.WEISTITL STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPFTITL 2 BINDING TO LRP5/6.REF DEV.CELL V. 21 862 2011REFN ISSN 1534-5807PMID 22000856DOI 10.1016/J.DEVCEL.2011.09.003 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ytv CSDE1 solution structure of the fifth cold-shock domain of the human kiaa0885 protein (unr protein) -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,AUTH 2 S.WATANABE,T.HARADA,A.TANAKA,O.OHARA,T.KIGAWA,S.YOKOYAMATITL THE NMR SOLUTION STRUCTURES OF THE FIVE CONSTITUENTTITL 2 COLD-SHOCK DOMAINS (CSD) OF THE HUMAN UNR (UPSTREAM OFTITL 3 N-RAS) PROTEIN.REF J.STRUCT.FUNCT.GENOM. V. 11 181 2010REFN ISSN 1345-711XPMID 20213426DOI 10.1007/S10969-010-9081-Z Variant […]
General Structure Information 2gqm SCO1 solution structure of human cu(i)-sco1 -1.0Å AUTH L.BANCI,I.BERTINI,V.CALDERONE,S.CIOFI-BAFFONI,AUTH 2 S.MANGANI,M.MARTINELLI,P.PALUMAA,S.WANGTITL A HINT FOR THE FUNCTION OF HUMAN SCO1 FROMTITL 2 DIFFERENT STRUCTURES.REF PROC.NATL.ACAD.SCI.USA V. 103 8595 2006REFN ISSN 0027-8424PMID 16735468DOI 10.1073/PNAS.0601375103 Variant Set Distributions Mapped Variants
General Structure Information 2xah KDM1A crystal structure of lsd1-corest in complex with (+)- trans-2-phenylcyclopropyl-1-amine 3.1Å AUTH C.BINDA,S.VALENTE,M.ROMANENGHI,S.PILOTTO,R.CIRILLI,AUTH 2 A.KARYTINOS,G.CIOSSANI,O.A.BOTRUGNO,F.FORNERIS,AUTH 3 M.TARDUGNO,D.E.EDMONDSON,S.MINUCCI,A.MATTEVI,A.MAITITL BIOCHEMICAL, STRUCTURAL, AND BIOLOGICAL EVALUATIONTITL 2 OF TRANYLCYPROMINE DERIVATIVES AS INHIBITORS OFTITL 3 HISTONE DEMETHYLASES LSD1 AND LSD2.REF J.AM.CHEM.SOC. V. 132 6827 2010REFN ISSN 0002-7863PMID 20415477DOI 10.1021/JA101557K Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3uo9 GLS crystal structure of human gac in complex with glutamate and bptes 2.3Å AUTH B.DELABARRE,S.GROSS,C.FANG,Y.GAO,A.JHA,F.JIANG,J.SONG J,AUTH 2 W.WEI,J.B.HUROVTITL FULL-LENGTH HUMAN GLUTAMINASE IN COMPLEX WITH AN ALLOSTERICTITL 2 INHIBITOR.REF BIOCHEMISTRY V. 50 10764 2011REFN ISSN 0006-2960PMID 22049910DOI 10.1021/BI201613D Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2di9 FLNB solution structure of the 9th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 9TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zjy IPO13 crystal structure of importin 13 – rangtp – eif1a complex 3.6Å AUTH M.GRUNWALD,D.LAZZARETTI,F.BONOTITL STRUCTURAL BASIS FOR THE NUCLEAR EXPORT ACTIVITY OFTITL 2 IMPORTIN13.REF EMBO J. V. 32 899 2013REFN ISSN 0261-4189PMID 23435562DOI 10.1038/EMBOJ.2013.29 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants