Assessment of Structural Intolerance and Durability
General Structure Information 1h95 YBX1 solution structure of the single-stranded dna-binding cold shock domain (csd) of human y-box protein 1 (yb1) determined by nmr (10 lowest energy structures) -1.0Å AUTH C.P.A.M.KLOKS,C.A.E.M.SPRONK,E.LASONDER,A.HOFFMANN,AUTH 2 G.W.VUISTER,S.GRZESIEK,C.W.HILBERSTITL THE SOLUTION STRUCTURE AND DNA-BINDING PROPERTIESTITL 2 OF THE COLD-SHOCK DOMAIN OF THE HUMAN Y-BOXTITL 3 PROTEIN YB-1.REF J.MOL.BIOL. V. 316 317 […]
General Structure Information 2doa ELL solution structure of the helical domain in human eleven- nineteen lysine-rich leukemia protein ell -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HELICAL DOMAIN IN HUMANTITL 2 ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN ELLREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2o94 HDAC4 the 97h/f mutant structure of a glutamine-rich domain from histone deacetylase 4 3.0Å AUTH L.GUO,A.HAN,D.L.BATES,J.CAO,L.CHENTITL CRYSTAL STRUCTURE OF A CONSERVED N-TERMINAL DOMAINTITL 2 OF HISTONE DEACETYLASE 4 REVEALS FUNCTIONALTITL 3 INSIGHTS INTO GLUTAMINE-RICH DOMAINS.REF PROC.NATL.ACAD.SCI.USA V. 104 4297 2007REFN ISSN 0027-8424PMID 17360518DOI 10.1073/PNAS.0608041104 Variant Set Distributions Mapped Variants
General Structure Information 2x4x BRPF1 molecular basis of histone h3k36me3 recognition by the pwwp domain of brpf1. 1.85Å AUTH A.VEZZOLI,N.BONADIES,M.D.ALLEN,S.M.V.FREUND,AUTH 2 C.M.SANTIVERI,B.KVINLAUG,B.J.P.HUNTLY,B.GOTTGENS,AUTH 3 M.BYCROFTTITL MOLECULAR BASIS OF HISTONE H3K36ME3 RECOGNITION BYTITL 2 THE PWWP DOMAIN OF BRPF1.REF NAT.STRUCT.MOL.BIOL. V. 17 617 2010REFN ISSN 1545-9993PMID 20400950DOI 10.1038/NSMB.1797 Variant Set Distributions Mapped Variants
General Structure Information 3n5u PPP1CA crystal structure of an rb c-terminal peptide bound to the catalytic subunit of pp1 3.2Å AUTH A.HIRSCHI,M.CECCHINI,R.C.STEINHARDT,M.R.SCHAMBER,F.A.DICK,AUTH 2 S.M.RUBINTITL AN OVERLAPPING KINASE AND PHOSPHATASE DOCKING SITE REGULATESTITL 2 ACTIVITY OF THE RETINOBLASTOMA PROTEIN.REF NAT.STRUCT.MOL.BIOL. V. 17 1051 2010REFN ISSN 1545-9993PMID 20694007DOI 10.1038/NSMB.1868 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2c35 POLR2G subunits rpb4 and rpb7 of human rna polymerase ii 2.7Å AUTH H.MEKA,F.WERNER,S.C.CORDELL,S.ONESTI,P.BRICKTITL CRYSTAL STRUCTURE AND RNA BINDING OF THE RPB4/RPB7TITL 2 SUBUNITS OF HUMAN RNA POLYMERASE II.REF NUCLEIC ACIDS RES. V. 33 6435 2005REFN ISSN 0305-1048PMID 16282592DOI 10.1093/NAR/GKI945 Variant Set Distributions Mapped Variants
General Structure Information 2iu1 EIF5 crystal structure of eif5 c-terminal domain 1.8Å AUTH C.BIENIOSSEK,P.SCHUTZ,M.BUMANN,A.LIMACHER,I.USON,AUTH 2 U.BAUMANNTITL THE CRYSTAL STRUCTURE OF THE CARBOXY-TERMINALTITL 2 DOMAIN OF HUMAN TRANSLATION INITIATION FACTORTITL 3 EIF5.REF J.MOL.BIOL. V. 360 457 2006REFN ISSN 0022-2836PMID 16781736DOI 10.1016/J.JMB.2006.05.021 Variant Set Distributions Mapped Variants
General Structure Information 2xeu RNF4 ring domain 1.5Å AUTH A.PLECHANOVOVA,E.G.JAFFRAY,S.A.MCMAHON,K.A.JOHNSON,AUTH 2 I.NAVRATILOVA,J.H.NAISMITH,R.T.HAYTITL MECHANISM OF UBIQUITYLATION BY DIMERIC RING LIGASE RNF4REF NAT.STRUCT.MOL.BIOL. V. 18 1052 2011REFN ISSN 1545-9993PMID 21857666DOI 10.1038/NSMB.2108 Variant Set Distributions Mapped Variants
General Structure Information 2djn DLX5 the solution structure of the homeobox domain of human homeobox protein dlx-5 -1.0Å AUTH A.SASAGAWA,S.OHNISHI,N.TOCHIO,K.SAITO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OFTITL 2 HUMAN HOMEOBOX PROTEIN DLX-5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dju BTG2 crystal structure of human btg2 2.26Å AUTH X.YANG,M.MORITA,H.WANG,T.SUZUKI,W.YANG,Y.LUO,AUTH 2 C.ZHAO,Y.YU,M.BARTLAM,T.YAMAMOTO,Z.RAOTITL CRYSTAL STRUCTURES OF HUMAN BTG2 AND MOUSE TIS21TITL 2 INVOLVED IN SUPPRESSION OF CAF1 DEADENYLASETITL 3 ACTIVITYREF NUCLEIC ACIDS RES. V. 36 6872 2008REFN ISSN 0305-1048PMID 18974182DOI 10.1093/NAR/GKN825 Variant Set Distributions Mapped Variants