Assessment of Structural Intolerance and Durability
General Structure Information 3ue2 PUF60 crystal structure of a rna binding domain of poly-u binding splicing factor 60kda (puf60) from homo sapiens at 1.23 a resolution 1.23Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF POLY-U BINDINGTITL 2 SPLICING FACTOR 60KDA (PUF60) FROM […]
General Structure Information 3hd6 RHCG crystal structure of the human rhesus glycoprotein rhcg 2.1Å AUTH F.GRUSWITZ,S.CHAUDHARY,J.D.HO,A.SCHLESSINGER,B.PEZESHKI,AUTH 2 C.M.HO,A.SALI,C.M.WESTHOFF,R.M.STROUDTITL FUNCTION OF HUMAN RH BASED ON STRUCTURE OF RHCG AT 2.1 A.REF PROC.NATL.ACAD.SCI.USA V. 107 9638 2010REFN ISSN 0027-8424PMID 20457942DOI 10.1073/PNAS.1003587107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2osg TJP2 solution structure and binding property of the domain- swapped dimer of zo2pdz2 -1.0Å AUTH J.W.WU,Y.S.YANG,J.H.ZHANG,P.JI,W.J.DU,P.JIANG,AUTH 2 D.H.XIE,H.D.HUANG,M.WU,G.Z.ZHANG,J.H.WU,Y.Y.SHITITL DOMAIN-SWAPPED DIMERIZATION OF THE SECOND PDZTITL 2 DOMAIN OF ZO2 MAY PROVIDE A STRUCTURAL BASIS FORTITL 3 THE POLYMERIZATION OF CLAUDINSREF J.BIOL.CHEM. V. 282 35988 2007REFN ISSN 0021-9258PMID 17897942DOI 10.1074/JBC.M703826200 Variant Set Distributions […]
General Structure Information 2ltm NFU1 solution nmr structure of nfu1 iron-sulfur cluster scaffold homolog from homo sapiens, northeast structural genomics consortium (nesg) target hr2876b -1.0Å AUTH G.LIU,R.XIAO,H.JANJUA,K.HAMILTON,R.SHASTRY,E.KOHAN,AUTH 2 T.B.ACTON,J.K.EVERETT,H.LEE,Y.J.HUANG,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF NFU1 IRON-SULFUR CLUSTER SCAFFOLDTITL 2 HOMOLOG FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICSTITL 3 CONSORTIUM (NESG) TARGET HR2876BREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 2h1s GRHPR crystal structure of a glyoxylate/hydroxypyruvate reductase from homo sapiens 2.45Å AUTH E.BITTO,G.E.WESENBERG,G.N.PHILLIPS JR.,C.A.BINGMAN,AUTH 2 CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL CRYSTAL STRUCTURE OF A GLYOXYLATE/HYDROXYPYRUVATE REDUCTASETITL 2 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kkq MYOT solution nmr structure of the ig-like c2-type 2 domain of human myotilin. northeast structural genomics target hr3158. -1.0Å AUTH P.ROSSI,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE IG-LIKE C2-TYPE 2TITL 2 DOMAIN OF HUMAN MYOTILIN. NORTHEAST STRUCTURALTITL 3 GENOMICS TARGET HR3158.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2b1u CALML5 solution structure of calmodulin-like skin protein c terminal domain -1.0Å AUTH E.BABINI,I.BERTINI,F.CAPOZZI,E.CHIRIVINO,C.LUCHINATTITL A STRUCTURAL AND DYNAMIC CHARACTERIZATION OF THETITL 2 EF-HAND PROTEIN CLSP.REF STRUCTURE V. 14 1029 2006REFN ISSN 0969-2126PMID 16765896DOI 10.1016/J.STR.2006.04.004 Variant Set Distributions Mapped Variants
General Structure Information 1w0b AHSP solution structure of the human alpha-hemoglobin stabilizing protein (ahsp) p30a mutant -1.0Å AUTH C.M.SANTIVERI,J.M.PEREZ-CANADILLAS,M.K.VADIVELU,AUTH 2 M.D.ALLEN,T.J.RUTHERFORD,N.A.WATKINS,M.BYCROFTTITL NMR STRUCTURE OF THE ALPHA-HEMOGLOBIN CHAPERONETITL 2 AHSP: INSIGHTS INTO CONFORMATIONAL HETEROGENEITYTITL 3 AND BINDINGREF J.BIOL.CHEM. V. 279 34963 2004REFN ISSN 0021-9258PMID 15178680DOI 10.1074/JBC.M405016200 Variant Set Distributions Mapped Variants
General Structure Information 2kxc BAIAP2L1 1h, 13c, and 15n chemical shift assignments for irtks-sh3 and espfu- r47 complex -1.0Å AUTH O.AITIO,M.HELLMAN,A.KAZLAUSKAS,D.F.VINGADASSALOM,J.M.LEONG,AUTH 2 K.SAKSELA,P.PERMITITL RECOGNITION OF TANDEM PXXP MOTIFS AS A UNIQUE SRC HOMOLOGYTITL 2 3-BINDING MODE TRIGGERS PATHOGEN-DRIVEN ACTIN ASSEMBLYREF PROC.NATL.ACAD.SCI.USA V. 107 21743 2010REFN ISSN 0027-8424PMID 21098279DOI 10.1073/PNAS.1010243107 Variant Set Distributions Mapped Variants
General Structure Information 2kn6 PYCARD structure of full-length human asc (apoptosis-associated speck-like protein containing a card) -1.0Å AUTH E.DE ALBATITL STRUCTURE AND INTERDOMAIN DYNAMICS OF APOPTOSIS-ASSOCIATEDTITL 2 SPECK-LIKE PROTEIN CONTAINING A CARD (ASC)REF J.BIOL.CHEM. V. 284 32932 2009REFN ISSN 0021-9258PMID 19759015DOI 10.1074/JBC.M109.024273 Variant Set Distributions Mapped Variants