Assessment of Structural Intolerance and Durability
General Structure Information 2eqs DHX8 solution structure of the s1 rna binding domain of human atp-dependent rna helicase dhx8 -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE S1 RNA BINDING DOMAIN OFTITL 2 HUMAN ATP-DEPENDENT RNA HELICASE DHX8REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dt6 SF3A1 solution structure of the first surp domain of human splicing factor sf3a120 -1.0Å AUTH K.KUWASAKO,F.HE,M.INOUE,A.TANAKA,S.SUGANO,AUTH 2 P.GUENTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE SURP DOMAINS AND THETITL 2 SUBUNIT-ASSEMBLY MECHANISM WITHIN THE SPLICINGTITL 3 FACTOR SF3A COMPLEX IN 17S U2 SNRNPREF STRUCTURE V. 14 1677 2006REFN ISSN 0969-2126PMID 17098193DOI 10.1016/J.STR.2006.09.009 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2epw ZNF268 solution structure of the 24th c2h2 type zinc finger domain of zinc finger protein 268 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 24TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 268REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l1i HLTF nmr structure of the hltf hiran domain -1.0Å AUTH D.NECULAI,I.BEZSONOVA,J.WEIGELT,C.BOUNTRA,A.EDWARDS,AUTH 2 C.ARROWSMITH,S.DHE-PAGANONTITL NMR STRUCTURE OF THE HLTF HIRAN DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mq4 GRM7 metabotropic glutamate receptor mglur7 complexed with ly341495 antagonist 2.8Å AUTH E.DOBROVETSKY,G.KHUTORESKAYA,A.SEITOVA,H.HE,A.M.EDWARDS,AUTH 2 C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,D.COSSAR,A.BOCHKAREVTITL MGLUR7 COMPLEXED WITH LY341495REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2d7o FLNC solution structure of the 17th filamin domain from human filamin c -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 17TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4o2w HERC1 crystal structure of the third rcc1-like domain of herc1 2.0Å AUTH J.HU,A.DONG,Y.LI,J.R.WALKER,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,Y.TONG,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF THE THIRD RCC1-LIKE DOMAIN OF HERC1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants