Assessment of Structural Intolerance and Durability
General Structure Information 2d8z FHL2 solution structure of the third lim domain of four and a half lim domains protein 2 (fhl-2) -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD LIM DOMAIN OF FOURTITL 2 AND A HALF LIM DOMAINS PROTEIN 2 (FHL-2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e7c MYBPC2 solution structure of the 6th ig-like domain from human myosin-binding protein c, fast-type -1.0Å AUTH X.R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 6TH IG-LIKE DOMAIN FROMTITL 2 HUMAN MYOSIN-BINDING PROTEIN C, FAST-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2he2 DLG2 crystal structure of the 3rd pdz domain of human discs large homologue 2, dlg2 1.5Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,AUTH 2 C.PHILLIPS,C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINEDTITL 2 WITH THE HELP OF SELF-BINDING C-TERMINALTITL 3 EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped […]
General Structure Information 1wgr GRB7 solution structure of the ra domain of human grb7 protein -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN OF HUMAN GRB7TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2a8b PTPRR crystal structure of the catalytic domain of human tyrosine phosphatase receptor, type r 2.3Å AUTH J.ESWARAN,J.P.VON KRIES,B.MARSDEN,E.LONGMAN,J.E.DEBRECZENI,AUTH 2 E.UGOCHUKWU,A.TURNBULL,W.H.LEE,S.KNAPP,A.J.BARRTITL CRYSTAL STRUCTURES AND INHIBITOR IDENTIFICATION FOR PTPN5,TITL 2 PTPRR AND PTPN7: A FAMILY OF HUMAN MAPK-SPECIFIC PROTEINTITL 3 TYROSINE PHOSPHATASES.REF BIOCHEM.J. V. 395 483 2006REFN ISSN 0264-6021PMID 16441242DOI 10.1042/BJ20051931 Variant Set […]
General Structure Information 2ebt KLF5 solution structure of three tandem repeats of zf-c2h2 domains from human kruppel-like factor 5 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THREE TANDEM REPEATS OFTITL 2 ZF-C2H2 DOMAINS FROM HUMAN KRUPPEL-LIKE FACTOR 5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ecs EIF2B1 crystal structure of human eif2b alpha 2.65Å AUTH T.B.HIYAMA,T.ITO,H.IMATAKA,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HUMAN TRANSLATIONTITL 2 INITIATION FACTOR 2BREF J.MOL.BIOL. V. 392 937 2009REFN ISSN 0022-2836PMID 19631657DOI 10.1016/J.JMB.2009.07.054 Variant Set Distributions Mapped Variants
General Structure Information 1y7x MVP solution structure of a two-repeat fragment of major vault protein -1.0Å AUTH G.KOZLOV,O.VAVELYUK,O.MINAILIUC,D.BANVILLE,AUTH 2 K.GEHRING,I.EKIELTITL SOLUTION STRUCTURE OF A TWO-REPEAT FRAGMENT OFTITL 2 MAJOR VAULT PROTEIN.REF J.MOL.BIOL. V. 356 444 2006REFN ISSN 0022-2836PMID 16373071DOI 10.1016/J.JMB.2005.11.064 Variant Set Distributions Mapped Variants
General Structure Information 2k9u FLNC solution nmr structure of the filamin-migfilin complex -1.0Å AUTH S.S.ITHYCHANDA,M.DAS,Y.Q.MA,K.DING,X.WANG,S.GUPTA,C.WU,AUTH 2 E.F.PLOW,J.QINTITL MIGFILIN, A MOLECULAR SWITCH IN REGULATION OF INTEGRINTITL 2 ACTIVATION.REF J.BIOL.CHEM. V. 284 4713 2009REFN ISSN 0021-9258PMID 19074766DOI 10.1074/JBC.M807719200 Variant Set Distributions Mapped Variants
General Structure Information 3f31 SPTAN1 crystal structure of the n-terminal region of alphaii-spectrin tetramerization domain 2.3Å AUTH S.MEHBOOB,Y.SONG,M.WITEK,F.LONG,B.D.SANTARSIERO,AUTH 2 M.E.JOHNSON,L.W.FUNGTITL CRYSTAL STRUCTURE OF THE NONERYTHROID ALPHA-SPECTRINTITL 2 TETRAMERIZATION SITE REVEALS DIFFERENCES BETWEEN ERYTHROIDTITL 3 AND NONERYTHROID SPECTRIN TETRAMER FORMATION.REF J.BIOL.CHEM. V. 285 14572 2010REFN ISSN 0021-9258PMID 20228407DOI 10.1074/JBC.M109.080028 Variant Set Distributions Mapped Variants