Assessment of Structural Intolerance and Durability
General Structure Information 2yre FBXO30 solution structure of the zinc finger domains (1-87) from human f-box only protein -1.0Å AUTH T.NAGASHIMA,T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC FINGER DOMAINSTITL 2 (1-87) FROM HUMAN F-BOX ONLY PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4ii1 ZGPAT crystal structure of the zinc finger of zgpat 2.65Å AUTH C.BIAN,W.TEMPEL,A.DONG,X.CHAO,M.FU,A.K.WERNIMONT,C.BOUNTRA,AUTH 2 J.WEIGELT,C.H.ARROWSMITH,A.M.EDWARDS,J.MINTITL CRYSTAL STRUCTURE OF THE ZINC FINGER OF ZGPATREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ysm KMT2C solution structure of the first and second phd domain from myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND SECOND PHDTITL 2 DOMAIN FROM MYELOID/LYMPHOID OR MIXED-LINEAGETITL 3 LEUKEMIA PROTEIN 3 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3hmh TAF1L crystal structure of the second bromodomain of human tbp-associated factor rna polymerase 1-like (taf1l) 2.05Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 3icu RNF128 protease-associated domain of the e3 ligase grail 2.1Å AUTH J.R.WALKER,L.YERMEKBAYEVA,A.SEITOVA,J.WEIGELT,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL PA DOMAIN OF THE E3 LIGASE GRAILREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2eoz ZNF473 solution structure of the c2h2 type zinc finger (region 809- 841) of human zinc finger protein 473 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 809-841) OF HUMAN ZINC FINGER PROTEIN 473REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d88 MICAL3 solution structure of the ch domain from human mical-3 protein -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMANTITL 2 MICAL-3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3smp PANK1 monoclinic crystal structure of human pantothenate kinase 1 alpha 1.9Å AUTH X.GUAN,W.TEMPEL,B.HONG,A.K.WERNIMONT,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL MONOCLINIC CRYSTAL STRUCTURE OF HUMAN PANTOTHENATE KINASE 1TITL 2 ALPHAREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3pg6 DTX3L the carboxyl terminal domain of human deltex 3-like 1.7Å AUTH J.OBIERO,J.R.WALKER,S.DHE-PAGANONTITL FOLD OF THE CONSERVED DTC DOMAIN IN DELTEX PROTEINS.REF PROTEINS V. 80 1495 2012REFN ISSN 0887-3585PMID 22411408DOI 10.1002/PROT.24054 Variant Set Distributions Mapped Variants
General Structure Information 2d89 EHBP1 solution structure of the ch domain from human eh domain binding protein 1 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMAN EHTITL 2 DOMAIN BINDING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants