Assessment of Structural Intolerance and Durability
General Structure Information 1y6l UBE2E2 human ubiquitin conjugating enzyme e2e2 1.85Å AUTH Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,AUTH 2 G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,AUTH 3 C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANONTITL A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASETITL 2 STRUCTURE-FUNCTION SCREEN.REF MOL CELL PROTEOMICS V. 11 329 2012REFNPMID 22496338DOI 10.1074/MCP.O111.013706 Variant Set Distributions Mapped Variants
General Structure Information 3s8i DDI1 the retroviral-like protease (rvp) domain of human ddi1 1.7Å AUTH J.R.WALKER,A.ASINAS,A.DONG,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL RETROPEPSIN-LIKE DOMAIN OF HUMAN DDI1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3r0n PVRL2 crystal structure of the immunoglobulin variable domain of nectin-2 1.3Å AUTH D.SAMANTA,U.A.RAMAGOPAL,R.RUBINSTEIN,V.VIGDOROVICH,AUTH 2 S.G.NATHENSON,S.C.ALMOTITL STRUCTURE OF NECTIN-2 REVEALS DETERMINANTS OF HOMOPHILIC ANDTITL 2 HETEROPHILIC INTERACTIONS THAT CONTROL CELL-CELL ADHESION.REF PROC.NATL.ACAD.SCI.USA V. 109 14836 2012REFN ISSN 0027-8424PMID 22927415DOI 10.1073/PNAS.1212912109 Variant Set Distributions Mapped Variants
General Structure Information 1x4v ZFAND2B solution structure of the zf-an1 domain from human hypothetical protein loc130617 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-AN1 DOMAIN FROM HUMANTITL 2 HYPOTHETICAL PROTEIN LOC130617REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1olz SEMA4D the ligand-binding face of the semaphorins revealed by the high resolution crystal structure of sema4d 2.0Å AUTH C.A.LOVE,K.HARLOS,N.MAVADDAT,S.J.DAVIS,D.I.STUART,AUTH 2 E.Y.JONES,R.M.ESNOUFTITL THE LIGAND-BINDING FACE OF THE SEMAPHORINSTITL 2 REVEALED BY THE HIGH-RESOLUTION CRYSTAL STRUCTURETITL 3 OF SEMA4DREF NAT.STRUCT.BIOL. V. 10 843 2003REFN ISSN 1072-8368PMID 12958590DOI 10.1038/NSB977 Variant Set Distributions Ripley’s K […]
General Structure Information 2cto MAEL solution structure of the hmg box like domain from human hypothetical protein flj14904 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 Y.O.KAMATARI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HMG BOX LIKE DOMAIN FROMTITL 2 HUMAN HYPOTHETICAL PROTEIN FLJ14904REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×40 ARAP2 solution structure of the sam domain of human arap2 -1.0Å AUTH A.SASAGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SAM DOMAIN OF HUMAN ARAP2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1um1 RADIL solution structure of rsgi ruh-007, pdz domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,F.HAYASHI,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-007, A PDZ DOMAINTITL 2 IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2eko KAT5 solution structure of ruh-073, a pseudo chromo domain from human cdna -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RUH-073, A PSEUDO CHROMOTITL 2 DOMAIN FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2qq5 DHRS1 crystal structure of human sdr family member 1 1.8Å AUTH E.S.PILKA,V.HOZJAN,E.UGOCHUKWU,F.VON DELFT,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SDR FAMILY MEMBER 1.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants