Assessment of Structural Intolerance and Durability
General Structure Information 2ed0 ABI2 solution structure of the sh3 domain of abl interactor 2 (abelson interactor 2) -1.0Å AUTH H.ABE,N.TOCHIO,K.MIYAMOTO,K.SAITO,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF ABLTITL 2 INTERACTOR 2 (ABELSON INTERACTOR 2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ihx PRDM10 methyltransferase domain of human pr domain-containing protein 10 2.5Å AUTH M.F.AMAYA,L.DOMBROVSKI,S.NI,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,J.MIN,A.N.PLOTNIKOV,AUTH 3 H.WU,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL METHYLTRANSFERASE DOMAIN OF HUMAN PR DOMAIN-CONTAININGTITL 2 PROTEIN 10REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cpd A1CF solution structure of the rna recognition motif of human apobec-1 complementation factor, acf -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OFTITL 2 HUMAN APOBEC-1 COMPLEMENTATION FACTOR, ACFREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wel RBM12 solution structure of rna binding domain in np_006038 -1.0Å AUTH T.SOMEYA,Y.MUTO,T.NAGATA,S.SUZUKI,M.INOUE,T.KIGAWA,AUTH 2 T.TERADA,M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 NP_006038REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3n50 EBF3 human early b-cell factor 3 (ebf3) ipt/tig and hlhlh domains 3.1Å AUTH M.I.SIPONEN,M.WISNIEWSKA,L.LEHTIO,I.JOHANSSON,L.SVENSSON,AUTH 2 G.RASZEWSKI,L.NILSSON,M.SIGVARDSSON,H.BERGLUNDTITL STRUCTURAL DETERMINATION OF FUNCTIONAL DOMAINS IN EARLYTITL 2 B-CELL FACTOR (EBF) FAMILY OF TRANSCRIPTION FACTORS REVEALSTITL 3 SIMILARITIES TO REL DNA-BINDING PROTEINS AND A NOVELTITL 4 DIMERIZATION MOTIF.REF J.BIOL.CHEM. V. 285 25875 2010REFN ISSN 0021-9258PMID […]
General Structure Information 3ihl CTPS2 human ctps2 crystal structure 2.8Å AUTH M.MOCHE,M.I.SIPONEN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,A.KOTZSCH,T.KRAGH NIELSEN,T.NYMAN,C.PERSSON,AUTH 5 A.K.ROOS,J.SAGEMARK,H.SCHUELER,P.SCHUTZ,A.G.THORSELL,AUTH 6 L.TRESAUGUES,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL HUMAN CTPS2 CRYSTAL STRUCTUREREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cpy RBM12 solution structure of rna binding domain 3 in rna binding motif protein 12 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN 3 IN RNATITL 2 BINDING MOTIF PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wx7 UBQLN3 solution structure of the n-terminal ubiquitin-like domain in the human ubiquilin 3 (ubqln3) -1.0Å AUTH C.ZHAO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINALTITL 2 UBIQUITIN-LIKE DOMAIN IN THE HUMAN UBIQUILIN 3TITL 3 (UBQLN3)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2fv7 RBKS crystal structure of human ribokinase 2.1Å AUTH W.M.RABEH,W.TEMPEL,L.NEDYALKOVA,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARK,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN RIBOKINASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3s4y TPK1 crystal structure of human thiamin pyrophosphokinase 1 1.8Å AUTH L.SHEN,W.TEMPEL,Y.TONG,Y.LI,J.R.WALKER,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN THIAMIN PYROPHOSPHOKINASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants