Assessment of Structural Intolerance and Durability
General Structure Information 1fd0 RARG isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid sr11254 1.38Å AUTH B.KLAHOLZ,D.MORASTITL C-H…O HYDROGEN BONDS IN THE NUCLEAR RECEPTORTITL 2 RARGAMMA–A POTENTIAL TOOL FOR DRUG SELECTIVITY.REF STRUCTURE V. 10 1197 2002REFN ISSN 0969-2126PMID 12220491DOI 10.1016/S0969-2126(02)00828-6 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1uwy CPM crystal structure of human carboxypeptidase m 3.0Å AUTH D.REVERTER,K.MASKOS,F.TAN,R.SKIDGEL,W.BODETITL CRYSTAL STRUCTURE OF HUMAN CARBOXYPEPTIDASE M, ATITL 2 MEMBRANE-BOUND ENZYME THAT REGULATES PEPTIDETITL 3 HORMONE ACTIVITYREF J.MOL.BIOL. V. 338 257 2004REFN ISSN 0022-2836PMID 15066430DOI 10.1016/J.JMB.2004.02.058 Variant Set Distributions Mapped Variants
General Structure Information 1rk9 PVALB solution structure of human alpha-parvalbumin (minimized average structure) -1.0Å AUTH I.BAIG,I.BERTINI,C.DEL BIANCO,Y.K.GUPTA,Y.-M.LEE,AUTH 2 C.LUCHINAT,A.QUATTRONETITL PARAMAGNETISM-BASED REFINEMENT STRATEGY FOR THETITL 2 SOLUTION STRUCTURE OF HUMAN ALPHA-PARVALBUMINREF BIOCHEMISTRY V. 43 5562 2004REFN ISSN 0006-2960PMID 15122922DOI 10.1021/BI035879K Variant Set Distributions Mapped Variants
General Structure Information 1ttx OCM solution stucture of human beta parvalbumin (oncomodulin) refined with a paramagnetism based strategy -1.0Å AUTH E.BABINI,I.BERTINI,F.CAPOZZI,C.DEL BIANCO,AUTH 2 D.HOLLENDER,T.KISS,C.LUCHINAT,A.QUATTRONETITL SOLUTION STRUCTURE OF HUMAN BETA-PARVALBUMIN ANDTITL 2 STRUCTURAL COMPARISON WITH ITS PARALOGTITL 3 ALPHA-PARVALBUMIN AND WITH THEIR RAT ORTHOLOGS(,)REF BIOCHEMISTRY V. 43 16076 2004REFN ISSN 0006-2960PMID 15610002DOI 10.1021/BI048388O Variant Set Distributions […]
General Structure Information 3d24 ESRRA crystal structure of ligand-binding domain of estrogen- related receptor alpha (erralpha) in complex with the peroxisome proliferators-activated receptor coactivator- 1alpha box3 peptide (pgc-1alpha) 2.11Å AUTH H.GRESCHIK,M.ALTHAGE,R.FLAIG,Y.SATO,V.CHAVANT,AUTH 2 C.PELUSO-ILTIS,L.CHOULIER,P.CRONET,N.ROCHEL,AUTH 3 R.SCHULE,P.E.STROMSTEDT,D.MORASTITL COMMUNICATION BETWEEN THE ERR{ALPHA} HOMODIMERTITL 2 INTERFACE AND THE PGC-1{ALPHA} BINDING SURFACE VIATITL 3 THE HELIX 8-9 LOOP.REF J.BIOL.CHEM. V. […]
General Structure Information 1su3 MMP1 x-ray structure of human prommp-1: new insights into collagenase action 2.2Å AUTH D.JOZIC,G.BOURENKOV,N.H.LIM,R.VISSE,H.NAGASE,AUTH 2 W.BODE,K.MASKOSTITL X-RAY STRUCTURE OF HUMAN PROMMP-1: NEW INSIGHTSTITL 2 INTO PROCOLLAGENASE ACTIVATION AND COLLAGENTITL 3 BINDING.REF J.BIOL.CHEM. V. 280 9578 2005REFN ISSN 0021-9258PMID 15611040DOI 10.1074/JBC.M411084200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2gqm SCO1 solution structure of human cu(i)-sco1 -1.0Å AUTH L.BANCI,I.BERTINI,V.CALDERONE,S.CIOFI-BAFFONI,AUTH 2 S.MANGANI,M.MARTINELLI,P.PALUMAA,S.WANGTITL A HINT FOR THE FUNCTION OF HUMAN SCO1 FROMTITL 2 DIFFERENT STRUCTURES.REF PROC.NATL.ACAD.SCI.USA V. 103 8595 2006REFN ISSN 0027-8424PMID 16735468DOI 10.1073/PNAS.0601375103 Variant Set Distributions Mapped Variants
General Structure Information 2jsd MMP20 solution structure of mmp20 complexed with nngh -1.0Å AUTH Y.ARENDT,L.BANCI,I.BERTINI,F.CANTINI,R.COZZI,AUTH 2 R.DEL CONTE,L.GONNELLITITL CATALYTIC DOMAIN OF MMP20 (ENAMELYSIN) – THE NMRTITL 2 STRUCTURE OF A NEW MATRIX METALLOPROTEINASE.REF FEBS LETT. V. 581 4723 2007REFN ISSN 0014-5793PMID 17869250DOI 10.1016/J.FEBSLET.2007.08.069 Variant Set Distributions Mapped Variants
General Structure Information 2rli SCO2 solution structure of cu(i) human sco2 -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,AUTH 2 I.P.GEROTHANASSIS,I.LEONTARI,M.MARTINELLI,S.WANGTITL A STRUCTURAL CHARACTERIZATION OF HUMAN SCO2REF STRUCTURE V. 15 1132 2007REFN ISSN 0969-2126PMID 17850752DOI 10.1016/J.STR.2007.07.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kkr ATXN7 solution structure of sca7 zinc finger domain from human ataxin-7 protein -1.0Å AUTH J.BONNET,Y.WANG,A.ATKINSON,J.KOFFLER,C.ROMIER,A.HAMICHE,AUTH 2 L.TORA,D.DEVYS,B.KIEFFERTITL HISTONE DEUBIQUITINATION BY SAGA IS MODULATED BY ANTITL 2 ATYPICAL ZINC FINGER DOMAIN OF ATAXIN-7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants