General Structure Information
| PDB ID | 2rli |
| HGNC Gene Label(s) | SCO2 |
| Structure Name | solution structure of cu(i) human sco2 |
| Resolution | -1.0Å |
| Reference | AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,AUTH 2 I.P.GEROTHANASSIS,I.LEONTARI,M.MARTINELLI,S.WANGTITL A STRUCTURAL CHARACTERIZATION OF HUMAN SCO2REF STRUCTURE V. 15 1132 2007REFN ISSN 0969-2126PMID 17850752DOI 10.1016/J.STR.2007.07.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 167 |
| Number Of SNVs | 59 |
| Number Of Permutations | 11502 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.196 |
| p-value | 0.086 |
ClinVar
| Number Of Residues | 167 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1259 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.0 |
| p-value | 0.754 |
COSMIC
| Number Of Residues | 167 |
| Number Of SNVs | 3 |
| Number Of Permutations | 207 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.333 |
| p-value | 0.927 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of ClinVar SNVs | 7 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | -0.074 |
| p-value | 1.0 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.309 |
| p-value | 0.77 |