Assessment of Structural Intolerance and Durability
General Structure Information 2qs9 RBBP9 crystal structure of the human retinoblastoma-binding protein 9 (rbbp-9). nesg target hr2978 1.72Å AUTH S.M.VOROBIEV,M.SU,J.SEETHARAMAN,Y.J.HUANG,C.X.CHEN,AUTH 2 M.MAGLAQUI,H.JANJUA,M.PROUDFOOT,A.YAKUNIN,R.XIAO,AUTH 3 T.B.ACTON,G.T.MONTELIONE,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN RETINOBLASTOMA BINDINGTITL 2 PROTEIN 9.REF PROTEINS V. 74 526 2008REFN ISSN 0887-3585PMID 19004028DOI 10.1002/PROT.22278 Variant Set Distributions Mapped Variants
General Structure Information 2k6m SVIL solution structure of human supervillin headpiece -1.0Å AUTH J.W.BROWN,D.VARDAR-ULU,C.J.MCKNIGHTTITL HOW TO ARM A SUPERVILLIN: DESIGNING F-ACTIN BINDINGTITL 2 ACTIVITY INTO SUPERVILLIN HEADPIECE.REF J.MOL.BIOL. V. 393 608 2009REFN ISSN 0022-2836PMID 19683541DOI 10.1016/J.JMB.2009.08.018 Variant Set Distributions Mapped Variants
General Structure Information 2ee6 FLNB solution structure of the 21th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 21TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmb FLNB solution structure of the 15th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 15TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2fne MPDZ the crystal structure of the 13th pdz domain of mpdz 1.83Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,AUTH 2 C.PHILLIPS,C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINEDTITL 2 WITH THE HELP OF SELF-BINDING C-TERMINALTITL 3 EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 2v9s SLIT2 second lrr domain of human slit2 2.0Å AUTH C.MORLOT,N.M.THIELENS,R.B.RAVELLI,W.HEMRIKA,R.A.ROMIJN,AUTH 2 P.GROS,S.CUSACK,A.A.MCCARTHYTITL STRUCTURAL INSIGHTS INTO THE SLIT-ROBO COMPLEX.REF PROC.NAT.ACAD.SCI.USA V. 104 14923 2007REFN ISSN 0027-8424PMID 17848514DOI 10.1073/PNAS.0705310104 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2eed FLNB solution structure of the 24th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 24TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dic FLNB solution structure of the 12th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 12TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2o2t MPDZ the crystal structure of the 1st pdz domain of mpdz 2.7Å AUTH E.PAPAGRIGORIOU,C.GILEADI,C.PHILLIPS,J.ELKINS,C.JOHANSSON,AUTH 2 E.SALAH,P.SAVITSKY,G.BERRIDGE,D.A.DOYLETITL THE CRYSTAL STRUCTURE OF THE 1ST PDZ DOMAIN OF MPDZREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1rgw LDB3 solution structure of zasps pdz domain -1.0Å AUTH Y.AU,R.A.ATKINSON,R.GUERRINI,G.KELLY,C.JOSEPH,AUTH 2 S.R.MARTIN,F.W.MUSKETT,A.PALLAVICINI,G.FAULKNER,AUTH 3 A.PASTORETITL SOLUTION STRUCTURE OF ZASP PDZ DOMAIN;TITL 2 IMPLICATIONS FOR SARCOMERE ULTRASTRUCTURE ANDTITL 3 ENIGMA FAMILY REDUNDANCY.REF STRUCTURE V. 12 611 2004REFN ISSN 0969-2126PMID 15062084DOI 10.1016/J.STR.2004.02.019 Variant Set Distributions Mapped Variants