General Structure Information
| PDB ID | 2v9s |
| HGNC Gene Label(s) | SLIT2 |
| Structure Name | second lrr domain of human slit2 |
| Resolution | 2.0Å |
| Reference | AUTH C.MORLOT,N.M.THIELENS,R.B.RAVELLI,W.HEMRIKA,R.A.ROMIJN,AUTH 2 P.GROS,S.CUSACK,A.A.MCCARTHYTITL STRUCTURAL INSIGHTS INTO THE SLIT-ROBO COMPLEX.REF PROC.NAT.ACAD.SCI.USA V. 104 14923 2007REFN ISSN 0027-8424PMID 17848514DOI 10.1073/PNAS.0705310104 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 206 |
| Number Of SNVs | 47 |
| Number Of Permutations | 21682 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.213 |
| p-value | 0.004 |
COSMIC
| Number Of Residues | 206 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3183 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.133 |
| p-value | 0.827 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.666 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
