Assessment of Structural Intolerance and Durability
General Structure Information 2he3 GPX2 crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (gpx2) 2.1Å AUTH K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE SELENOCYSTEINE TO CYSTEINE MUTANTTITL 2 OF HUMAN GLUTATHIONINE PEROXIDASE 2 (GPX2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fe1 HSPA6 crystal structure of the human 70kda heat shock protein 6 (hsp70b) atpase domain in complex with adp and inorganic phosphate 2.2Å AUTH M.WISNIEWSKA,T.KARLBERG,L.LEHTIO,I.JOHANSSON,AUTH 2 T.KOTENYOVA,M.MOCHE,H.SCHUELERTITL CRYSTAL STRUCTURES OF THE ATPASE DOMAINS OF FOURTITL 2 HUMAN HSP70 ISOFORMS: HSPA1L/HSP70-HOM,TITL 3 HSPA2/HSP70-2, HSPA6/HSP70B, AND HSPA5/BIP/GRP78REF PLOS ONE V. 5 E8625 2010REFN ESSN […]
General Structure Information 2cq7 CRISP2 solution structure of rsgi ruh-032, a cystein-rich domain of crisp-2 from human cdna -1.0Å AUTH T.ABE,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-032, A CYSTEIN-RICHTITL 2 DOMAIN OF CRISP-2 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3hng FLT1 crystal structure of vegfr1 in complex with n-(4-chlorophenyl)-2- ((pyridin-4-ylmethyl)amino)benzamide 2.7Å AUTH L.TRESAUGUES,A.ROOS,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,M.MOCHE,T.NYMAN,C.PERSSON,T.KRAGH-NIELSEN,AUTH 5 A.KOTZCH,J.SAGEMARK,H.SCHUELER,P.SCHUTZ,M.I.SIPONEN,AUTH 6 L.SVENSSON,A.G.THORSELL,S.VAN DER BERG,J.WEIGELT,M.WELIN,AUTH 7 M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF VEGFR1 IN COMPLEX WITHTITL 2 N-(4-CHLOROPHENYL)-2-((PYRIDIN-4-YLMETHYL)AMINO)BENZAMIDEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 1rk9 PVALB solution structure of human alpha-parvalbumin (minimized average structure) -1.0Å AUTH I.BAIG,I.BERTINI,C.DEL BIANCO,Y.K.GUPTA,Y.-M.LEE,AUTH 2 C.LUCHINAT,A.QUATTRONETITL PARAMAGNETISM-BASED REFINEMENT STRATEGY FOR THETITL 2 SOLUTION STRUCTURE OF HUMAN ALPHA-PARVALBUMINREF BIOCHEMISTRY V. 43 5562 2004REFN ISSN 0006-2960PMID 15122922DOI 10.1021/BI035879K Variant Set Distributions Mapped Variants
General Structure Information 2q4g RNH1 ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease i 1.95Å AUTH R.J.JOHNSON,J.G.MCCOY,C.A.BINGMAN,G.N.PHILLIPS JR.,AUTH 2 R.T.RAINESTITL INHIBITION OF HUMAN PANCREATIC RIBONUCLEASE BY THE HUMANTITL 2 RIBONUCLEASE INHIBITOR PROTEIN.REF J.MOL.BIOL. V. 368 434 2007REFN ISSN 0022-2836PMID 17350650DOI 10.1016/J.JMB.2007.02.005 Variant Set Distributions Mapped Variants
General Structure Information 2fn4 RRAS the crystal structure of human ras-related protein, rras, in the gdp- bound state 1.65Å AUTH A.P.TURNBULL,J.M.ELKINS,C.GILEADI,N.BURGESS,E.SALAH,AUTH 2 E.PAPAGRIGORIOU,J.DEBRECZENI,F.VON DELFT,J.WEIGELT,AUTH 3 A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF HUMAN RAS-RELATED PROTEIN, RRAS, INTITL 2 THE GDP-BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yrq HMGB1 solution structure of the tandem hmg box domain from human high mobility group protein b1 -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TANDEM HMG BOX DOMAINTITL 2 FROM HUMAN HIGH MOBILITY GROUP PROTEIN B1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2edy PTPRF solution structures of the fn3 domain of human receptor- type tyrosine-protein phosphatase f -1.0Å AUTH M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE FREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ebl NR2F1 solution structure of the zinc finger, c4-type domain of human coup transcription factor 1 -1.0Å AUTH M.YONEYAMA,S.KOSHIBA,S.WATABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC FINGER, C4-TYPETITL 2 DOMAIN OF HUMAN COUP TRANSCRIPTION FACTOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants