Assessment of Structural Intolerance and Durability
General Structure Information 2p0w HAT1 human histone acetyltransferase 1 (hat1) 1.9Å AUTH H.WU,J.MIN,H.ZENG,P.LOPPNAU,J.WEIGELT,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN HISTONE ACETYLTRANSFERASE 1TITL 2 (HAT1) IN COMPLEX WITH ACETYLCOENZYME A AND HISTONE PEPTIDETITL 3 H4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2hhl CTDSPL crystal structure of the human small ctd phosphatase 3 isoform 1 2.1Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,AUTH 2 T.P.DILORENZO,V.MALASHKEVICH,S.R.WASSERMAN,AUTH 3 S.SWAMINATHAN,S.ESWARAMOORTHY,R.AGARWAL,D.KUMARAN,AUTH 4 M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,J.ALVARADO,AUTH 5 U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 6 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Mapped Variants
General Structure Information 2dk2 HNRNPR solution structure of rrm domain in heterogeneous nuclear ribonucleoprotein r (hnrnp r) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RRM DOMAIN IN HETEROGENEOUSTITL 2 NUCLEAR RIBONUCLEOPROTEIN R (HNRNP R)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3cok PLK4 crystal structure of plk4 kinase 2.25Å AUTH S.ATWELL,S.K.BURLEY,A.HOULE,B.LEON,L.A.PELLETIER,AUTH 2 J.M.SAUDERTITL CRYSTAL STRUCTURE OF PLK4 KINASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2csp RIMBP2 solution structure of the fniii domain of human rim-binding protein 2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FNIII DOMAIN OF HUMANTITL 2 RIM-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2g76 PHGDH crystal structure of human 3-phosphoglycerate dehydrogenase 1.7Å AUTH A.P.TURNBULL,E.SALAH,P.SAVITSKY,O.GILEADI,F.VON DELFT,AUTH 2 A.EDWARDS,C.ARROWSMITH,J.WEIGELT,M.SUNDSTROM,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN 3-PHOSPHOGLYCERATE DEHYDROGENASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z5f SULT1B1 human sulfotransferase sult1b1 in complex with pap 2.1Å AUTH L.DOMBROVSKI,A.DONG,A.BOCHKAREV,A.N.PLOTNIKOVTITL CRYSTAL STRUCTURES OF HUMAN SULFOTRANSFERASESTITL 2 SULT1B1 AND SULT1C1 COMPLEXED WITH THE COFACTORTITL 3 PRODUCT ADENOSINE-3-5-DIPHOSPHATE (PAP)REF PROTEINS V. 64 1091 2006REFN ISSN 0887-3585PMID 16804942DOI 10.1002/PROT.21048 Variant Set Distributions Mapped Variants
General Structure Information 2a1x PHYH human phytanoyl-coa 2-hydroxylase in complex with iron and 2- oxoglutarate 2.5Å AUTH M.A.MCDONOUGH,K.L.KAVANAGH,D.BUTLER,T.SEARLES,U.OPPERMANN,AUTH 2 C.J.SCHOFIELDTITL STRUCTURE OF HUMAN PHYTANOYL-COA 2-HYDROXYLASE IDENTIFIESTITL 2 MOLECULAR MECHANISMS OF REFSUM DISEASEREF J.BIOL.CHEM. V. 280 41101 2005REFN ISSN 0021-9258PMID 16186124DOI 10.1074/JBC.M507528200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 4en0 TNFSF14 crystal structure of light 2.59Å AUTH W.LIU,C.ZHAN,H.CHENG,P.R.KUMAR,J.B.BONANNO,S.G.NATHENSON,AUTH 2 S.C.ALMOTITL MECHANISTIC BASIS FOR FUNCTIONAL PROMISCUITY IN THE TNF ANDTITL 2 TNF RECEPTOR SUPERFAMILIES: STRUCTURE OF THE LIGHT:DCR3TITL 3 ASSEMBLY.REF STRUCTURE V. 22 1252 2014REFN ISSN 0969-2126PMID 25087510DOI 10.1016/J.STR.2014.06.013 Variant Set Distributions Mapped Variants
General Structure Information 1wyq SPTBN2 solution structure of the second ch domain of human spectrin beta chain, brain 2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND CH DOMAIN OFTITL 2 HUMAN SPECTRIN BETA CHAIN, BRAIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants