Assessment of Structural Intolerance and Durability
General Structure Information 2pny IDI2 structure of human isopentenyl-diphosphate delta-isomerase 2 1.81Å AUTH J.R.WALKER,T.DAVIS,C.BUTLER-COLE,J.WEIGELT,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL STRUCTURE OF THE HUMAN ISOPENTENYL-DIPHOSPHATETITL 2 DELTA-ISOMERASE 2.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ld6 CYP51A1 crystal structure of human lanosterol 14alpha-demethylase (cyp51) in complex with ketoconazole 2.8Å AUTH N.STRUSHKEVICH,S.A.USANOV,H.W.PARKTITL STRUCTURAL BASIS OF HUMAN CYP51 INHIBITION BY ANTIFUNGALTITL 2 AZOLES.REF J.MOL.BIOL. V. 397 1067 2010REFN ISSN 0022-2836PMID 20149798DOI 10.1016/J.JMB.2010.01.075 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ch4 PMVK the crystal structure of human phosphomavelonate kinase at 1.8 a resolution 1.76Å AUTH Q.CHANG,X.-X.YAN,S.-Y.GU,J.-F.LIU,D.-C.LIANGTITL CRYSTAL STRUCTURE OF HUMAN PHOSPHOMAVELONATETITL 2 KINASE AT 1.8 A RESOLUTIONREF PROTEINS V. 73 254 2008REFN ISSN 0887-3585PMID 18618710DOI 10.1002/PROT.22151 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2ctj HDLBP solution structure of the 8th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 8TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ctl HDLBP solution structure of the 13th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 13TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ctl HDLBP solution structure of the 13th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 13TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ctl HDLBP solution structure of the 13th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 13TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants