Assessment of Structural Intolerance and Durability
General Structure Information 2vge PPP1R13L crystal structure of the c-terminal region of human iaspp 2.1Å AUTH R.A.ROBINSON,X.LU,E.Y.JONES,C.SIEBOLDTITL BIOCHEMICAL AND STRUCTURAL STUDIES OF ASPPTITL 2 PROTEINS REVEAL DIFFERENTIAL BINDING TO P53, P63TITL 3 AND P73REF STRUCTURE V. 16 259 2008REFN ISSN 0969-2126PMID 18275817DOI 10.1016/J.STR.2007.11.012 Variant Set Distributions Mapped Variants
General Structure Information 3nnc CELF1 crystal structure of cugbp1 rrm1/2-rna complex 2.2Å AUTH M.TEPLOVA,J.SONG,H.Y.GAW,A.TEPLOV,D.J.PATELTITL STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY THETITL 2 ALTERNATE-SPLICING REGULATOR CUG-BINDING PROTEIN 1.REF STRUCTURE V. 18 1364 2010REFN ISSN 0969-2126PMID 20947024DOI 10.1016/J.STR.2010.06.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3c0y HDAC7 crystal structure of catalytic domain of human histone deacetylase hdac7 2.1Å AUTH A.SCHUETZ,J.MIN,A.ALLALI-HASSANI,M.SCHAPIRA,AUTH 2 M.SHUEN,P.LOPPNAU,R.MAZITSCHEK,N.P.KWIATKOWSKI,AUTH 3 T.A.LEWIS,R.L.MAGLATHIN,T.H.MCLEAN,A.BOCHKAREV,AUTH 4 A.N.PLOTNIKOV,M.VEDADI,C.H.ARROWSMITHTITL HUMAN HDAC7 HARBORS A CLASS IIA HISTONETITL 2 DEACETYLASE-SPECIFIC ZINC BINDING MOTIF AND CRYPTICTITL 3 DEACETYLASE ACTIVITY.REF J.BIOL.CHEM. V. 283 11355 2008REFN ISSN 0021-9258PMID 18285338DOI 10.1074/JBC.M707362200 Variant Set Distributions Mapped Variants
General Structure Information 2v14 KIF16B kinesin 16b phox-homology domain (kif16b) 2.2Å AUTH N.R.BLATNER,M.I.WILSON,C.LEI,W.HONG,D.MURRAY,AUTH 2 R.L.WILLIAMS,W.CHOTITL THE STRUCTURAL BASIS OF NOVEL ENDOSOME ANCHORINGTITL 2 ACTIVITY OF KIF16B KINESIN.REF EMBO J. V. 26 3709 2007REFN ISSN 0261-4189PMID 17641687DOI 10.1038/SJ.EMBOJ.7601800 Variant Set Distributions Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ziv EME1 crystal structure of the mus81-eme1 complex 2.7Å AUTH J.H.CHANG,J.J.KIM,J.M.CHOI,J.H.LEE,Y.CHOTITL CRYSTAL STRUCTURE OF THE MUS81-EME1 COMPLEXREF GENES DEV. V. 22 1093 2008REFN ISSN 0890-9369PMID 18413719DOI 10.1101/GAD.1618708 Variant Set Distributions Mapped Variants
General Structure Information 3ff7 KLRG1 structure of nk cell receptor klrg1 bound to e-cadherin 1.8Å AUTH Y.LI,M.HOFMANN,Q.WANG,L.TENG,L.K.CHLEWICKI,AUTH 2 H.PIRCHER,R.A.MARIUZZATITL STRUCTURE OF NATURAL KILLER CELL RECEPTOR KLRG1TITL 2 BOUND TO E-CADHERIN REVEALS BASIS FORTITL 3 MHC-INDEPENDENT MISSING SELF RECOGNITION.REF IMMUNITY V. 31 35 2009REFN ISSN 1074-7613PMID 19604491DOI 10.1016/J.IMMUNI.2009.04.019 Variant Set Distributions Mapped Variants
General Structure Information 2jvz KHSRP solution nmr structure of the second and third kh domains of ksrp -1.0Å AUTH I.DIAZ-MORENO,D.HOLLINGWORTH,M.F.GARCIA-MAYORAL,AUTH 2 G.KELLY,S.MARTIN,C.Y.CHEN,A.RAMOSTITL SOLUTION NMR STRUCTURE OF THE SECOND AND THIRD KHTITL 2 DOMAINS OF KSRPREF TO BE PUBLISHED 2007REFN Variant Set Distributions Mapped Variants
General Structure Information 3siu PRPF31 structure of a hprp31-15.5k-u4atac 5 stem loop complex, monomeric form 2.63Å AUTH S.LIU,H.GHALEI,R.LUHRMANN,M.C.WAHLTITL STRUCTURAL BASIS FOR THE DUAL U4 AND U4ATAC SNRNA-BINDINGTITL 2 SPECIFICITY OF SPLICEOSOMAL PROTEIN HPRP31.REF RNA V. 17 1655 2011REFN ISSN 1355-8382PMID 21784869DOI 10.1261/RNA.2690611 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3hbw FGF13 crystal structure of human fibroblast growth factor homologous factor 2a (fhf2a), also referred to as fibroblast growth factor 13a (fgf13a) 1.9Å AUTH R.GOETZ,K.DOVER,F.LAEZZA,N.SHTRAIZENT,X.HUANG,AUTH 2 D.TCHETCHIK,A.V.ELISEENKOVA,C.F.XU,T.A.NEUBERT,AUTH 3 D.M.ORNITZ,M.GOLDFARB,M.MOHAMMADITITL CRYSTAL STRUCTURE OF A FIBROBLAST GROWTH FACTORTITL 2 HOMOLOGOUS FACTOR (FHF) DEFINES A CONSERVED SURFACETITL 3 ON FHFS FOR BINDING AND MODULATION OF […]