Assessment of Structural Intolerance and Durability
General Structure Information 2ke5 RALB solution structure and dynamics of the small gtpase ralb in its active conformation: significance for effector protein binding -1.0Å AUTH R.B.FENWICK,S.PRASANNAN,L.J.CAMPBELL,D.NIETLISPACH,AUTH 2 K.A.EVETTS,J.CAMONIS,H.R.MOTT,D.OWENTITL SOLUTION STRUCTURE AND DYNAMICS OF THE SMALL GTPASETITL 2 RALB IN ITS ACTIVE CONFORMATION: SIGNIFICANCE FORTITL 3 EFFECTOR PROTEIN BINDINGREF BIOCHEMISTRY V. 48 2192 2009REFN ISSN 0006-2960PMID […]
General Structure Information 3ol2 PLXNB1 receptor-ligand structure of human semaphorin 4d with plexin b1. 2.99Å AUTH B.J.JANSSEN,R.A.ROBINSON,F.PEREZ-BRANGULI,C.H.BELL,AUTH 2 K.J.MITCHELL,C.SIEBOLD,E.Y.JONESTITL STRUCTURAL BASIS OF SEMAPHORIN-PLEXIN SIGNALLING.REF NATURE V. 467 1118 2010REFN ISSN 0028-0836PMID 20877282DOI 10.1038/NATURE09468 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4a9c INPPL1 crystal structure of human ship2 in complex with biphenyl 2,3,4,5,6-pentakisphosphate 2.1Å AUTH S.J.MILLS,C.PERSSON,G.COZIER,M.P.THOMAS,L.TRESAUGUES,AUTH 2 C.ERNEUX,A.M.RILEY,P.NORDLUND,B.V.L.POTTERTITL A SYNTHETIC POLYPHOSPHOINOSITIDE HEADGROUP SURROGATE INTITL 2 COMPLEX WITH SHIP2 PROVIDES A RATIONALE FOR DRUG DISCOVERY.REF ACS CHEM.BIOL. V. 7 822 2012REFN ISSN 1554-8929PMID 22330088DOI 10.1021/CB200494D Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]