General Structure Information
| PDB ID | 2ke5 |
| HGNC Gene Label(s) | RALB |
| Structure Name | solution structure and dynamics of the small gtpase ralb in its active conformation: significance for effector protein binding |
| Resolution | -1.0Å |
| Reference | AUTH R.B.FENWICK,S.PRASANNAN,L.J.CAMPBELL,D.NIETLISPACH,AUTH 2 K.A.EVETTS,J.CAMONIS,H.R.MOTT,D.OWENTITL SOLUTION STRUCTURE AND DYNAMICS OF THE SMALL GTPASETITL 2 RALB IN ITS ACTIVE CONFORMATION: SIGNIFICANCE FORTITL 3 EFFECTOR PROTEIN BINDINGREF BIOCHEMISTRY V. 48 2192 2009REFN ISSN 0006-2960PMID 19166349DOI 10.1021/BI802129D |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 174 |
| Number Of SNVs | 29 |
| Number Of Permutations | 8612 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.155 |
| p-value | 0.239 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 29 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.416 |
| p-value | 0.659 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
