Assessment of Structural Intolerance and Durability
General Structure Information 3fkc ZBTB33 crystal structure of human zinc finger and btb domain containing 33 1.7Å AUTH P.FILIPPAKOPOULOS,A.BULLOCK,T.KEATES,N.BURGESS-BROWN,AUTH 2 J.MUNIZ,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 3 C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN ZINC FINGER AND BTB DOMAINTITL 2 CONTAINING 33REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3un9 NLRX1 crystal structure of an immune receptor 2.65Å AUTH M.HONG,S.I.YOON,I.A.WILSONTITL STRUCTURE AND FUNCTIONAL CHARACTERIZATION OF THE RNA-BINDINGTITL 2 ELEMENT OF THE NLRX1 INNATE IMMUNE MODULATOR.REF IMMUNITY V. 36 337 2012REFN ISSN 1074-7613PMID 22386589DOI 10.1016/J.IMMUNI.2011.12.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wfv MAGI2 solution structure of the fifth pdz domain of human membrane associated guanylate kinase inverted-2 (kiaa0705 protein) -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH PDZ DOMAIN OFTITL 2 HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASETITL 3 INVERTED-2 (KIAA0705 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uep MAGI2 solution structure of the third pdz domain of human atrophin-1 interacting protein 1 (kiaa0705 protein) -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OFTITL 2 HUMAN ATROPHIN-1 INTERACTING PROTEIN 1 (KIAA0705TITL 3 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kiv ANKS1B aida-1 sam domain tandem -1.0Å AUTH A.KURABI,S.BRENER,M.MOBLI,J.J.KWAN,L.W.DONALDSONTITL A NUCLEAR LOCALIZATION SIGNAL AT THE SAM-SAM DOMAINTITL 2 INTERFACE OF AIDA-1 SUGGESTS A REQUIREMENT FORTITL 3 DOMAIN UNCOUPLING PRIOR TO NUCLEAR IMPORT.REF J.MOL.BIOL. V. 392 1168 2009REFN ISSN 0022-2836PMID 19666031DOI 10.1016/J.JMB.2009.08.004 Variant Set Distributions Mapped Variants
General Structure Information 4l7e HDDC2 three dimensional structure of mutant d78a of human hd domain- containing protein 2, genomics consortium (nesg) target hr6723 2.23Å AUTH A.KUZIN,M.SU,A..YAKUNIN,N.BELOGLAZOVA,J.SEETHARAMAN,AUTH 2 M.MAGLAQUI,R.XIAO,D.LEE,G.BROWN,R.FLICK,J.K.EVERETT,AUTH 3 T.B.ACTON,G.T.MONTELIONE,J.F.HUNT,L.TONG,AUTH 4 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)TITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6723REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2m76 CPT1C structure of the regulatory domain of human brain carnitine palmitoyltransferase 1 -1.0Å AUTH S.SAMANTA,A.J.SITU,T.S.ULMERTITL STRUCTURAL CHARACTERIZATION OF THE REGULATORY DOMAIN OFTITL 2 BRAIN CARNITINE PALMITOYLTRANSFERASE 1.REF BIOPOLYMERS V. 101 398 2014REFN ISSN 0006-3525PMID 24037959DOI 10.1002/BIP.22396 Variant Set Distributions Mapped Variants
General Structure Information 2p5s RASEF rab domain of human rasef in complex with gdp 2.15Å AUTH H.ZHU,J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL RAB DOMAIN OF HUMAN RASEF IN COMPLEX WITH GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1mi1 NBEA crystal structure of the ph-beach domain of human neurobeachin 2.9Å AUTH G.JOGL,Y.SHEN,D.GEBAUER,J.LI,K.WIEGMANN,H.KASHKAR,AUTH 2 M.KRONKE,L.TONGTITL CRYSTAL STRUCTURE OF THE BEACH DOMAIN REVEALS ANTITL 2 UNUSUAL FOLD AND EXTENSIVE ASSOCIATION WITH ATITL 3 NOVEL PH DOMAIN.REF EMBO J. V. 21 4785 2002REFN ISSN 0261-4189PMID 12234919DOI 10.1093/EMBOJ/CDF502 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2d88 MICAL3 solution structure of the ch domain from human mical-3 protein -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMANTITL 2 MICAL-3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants