Assessment of Structural Intolerance and Durability
General Structure Information 2q9v MAGI1 crystal structure of the c890s mutant of the 4th pdz domain of human membrane associated guanylate kinase 2.0Å AUTH E.S.PILKA,V.HOZJAN,K.L.KAVANAGH,E.PAPAGRIGORIOU,C.COOPER,AUTH 2 J.M.ELKINS,D.A.DOYLE,F.VON DELFT,M.SUNDSTROM,C.A.ARROWSMITH,AUTH 3 J.WEIGELT,A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE C890S MUTANT OF THE 4TH PDZ DOMAINTITL 2 OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2p31 GPX7 crystal structure of human glutathione peroxidase 7 2.0Å AUTH K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE PEROXIDASE 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3oln UHRF2 crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf2 2.3Å AUTH J.R.WALKER,S.XUE,G.V.AVVAKUMOV,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE SET AND RING ASSOCIATED (SRA) DOMAIN OF HUMANTITL 2 UBIQUITIN-LIKE CONTAINING PHD AND RING FINGER DOMAINS 2TITL 3 (UHRF2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2h58 KIFC3 crystal structure of the kifc3 motor domain in complex with adp 1.85Å AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE KIFC3 MOTOR DOMAIN INTITL 2 COMPLEX WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3iv1 TSG101 coiled-coil domain of tumor susceptibility gene 101 2.5Å AUTH D.NECULAI,G.V.AVVAKUMOV,A.K.WERNIMONT,S.XUE,AUTH 2 J.R.WALKER,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL COILED-COIL DOMAIN OF HUMAN TSG101REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ow8 WDR61 crystal structure of the wd repeat-containing protein 61 2.3Å AUTH C.XU,J.MINTITL STRUCTURE AND FUNCTION OF WD40 DOMAIN PROTEINS.REF PROTEIN CELL V. 2 202 2011REFN ISSN 1674-800XPMID 21468892DOI 10.1007/S13238-011-1018-1 Variant Set Distributions Mapped Variants
General Structure Information 3hlt HDHD2 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 2 (hdhd2) 2.3Å AUTH E.UGOCHUKWU,N.SHAFQAT,W.W.YUE,R.COCKING,J.E.BRAY,AUTH 2 J.R.C.MUNIZ,T.KROJER,F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 J.WEIGELT,A.EDWARDS,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACID DEHALOGENASE-LIKETITL 2 HYDROLASE DOMAIN CONTAINING 2 (HDHD2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kdb HERPUD2 solution structure of human ubiquitin-like domain of herpud2_9_85, northeast structural genomics consortium (nesg) target ht53a -1.0Å AUTH R.DOHERTY,B.WU,C.FARES,A.LEMAK,A.GUTMANAS,A.SEMESI,A.YEE,AUTH 2 C.H.ARROWSMITH,S.DHE-PAGANONTITL STRUCTURE OF HUMAN HOMOCYSTEINE-INDUCIBLE, ENDOPLASMICTITL 2 RETICULUM STRESS-INDUCIBLE, UBIQUITIN-LIKE DOMAIN MEMBER 2TITL 3 (HERPUD2 OR HERP)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3emw SPSB2 crystal structure of human spla/ryanodine receptor domain and socs box containing 2 (spsb2) in complex with a 20-residue vasa peptide 1.8Å AUTH P.FILIPPAKOPOULOS,A.LOW,T.D.SHARPE,J.UPPENBERG,S.YAO,AUTH 2 Z.KUANG,P.SAVITSKY,R.S.LEWIS,S.E.NICHOLSON,R.S.NORTON,AUTH 3 A.N.BULLOCKTITL STRUCTURAL BASIS FOR PAR-4 RECOGNITION BY THE SPRY DOMAIN-TITL 2 AND SOCS BOX-CONTAINING PROTEINS SPSB1, SPSB2, AND SPSB4.REF J.MOL.BIOL. V. 401 389 2010REFN […]
General Structure Information 3ber DDX47 human dead-box rna-helicase ddx47, conserved domain i in complex with amp 1.4Å AUTH P.SCHUTZ,T.KARLBERG,S.VAN DEN BERG,R.COLLINS,L.LEHTIO,AUTH 2 M.HOGBOM,L.HOLMBERG-SCHIAVONE,W.TEMPEL,H.W.PARK,AUTH 3 M.HAMMARSTROM,M.MOCHE,A.G.THORSELL,H.SCHULERTITL COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX RNATITL 2 HELICASES.REF PLOS ONE V. 5 12791 2010REFN ESSN 1932-6203PMID 20941364DOI 10.1371/JOURNAL.PONE.0012791 Variant Set Distributions Mapped Variants