Assessment of Structural Intolerance and Durability
General Structure Information 2m85 SHPRH phd domain from human shprh -1.0Å AUTH L.E.MACHADO,Y.PUSTOVALOVA,A.C.KILE,A.POZHIDAEVA,AUTH 2 K.A.CIMPRICH,F.C.ALMEIDA,I.BEZSONOVA,D.M.KORZHNEVTITL PHD DOMAIN FROM HUMAN SHPRH.REF J.BIOMOL.NMR V. 56 393 2013REFN ISSN 0925-2738PMID 23907177DOI 10.1007/S10858-013-9758-2 Variant Set Distributions Mapped Variants
General Structure Information 1v5w DMC1 crystal structure of the human dmc1 protein 3.2Å AUTH T.KINEBUCHI,W.KAGAWA,R.ENOMOTO,K.TANAKA,K.MIYAGAWA,AUTH 2 T.SHIBATA,H.KURUMIZAKA,S.YOKOYAMATITL STRUCTURAL BASIS FOR OCTAMERIC RING FORMATION AND DNATITL 2 INTERACTION OF THE HUMAN HOMOLOGOUS-PAIRING PROTEIN DMC1REF MOL.CELL V. 14 363 2004REFN ISSN 1097-2765PMID 15125839DOI 10.1016/S1097-2765(04)00218-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 1v5w DMC1 crystal structure of the human dmc1 protein 3.2Å AUTH T.KINEBUCHI,W.KAGAWA,R.ENOMOTO,K.TANAKA,K.MIYAGAWA,AUTH 2 T.SHIBATA,H.KURUMIZAKA,S.YOKOYAMATITL STRUCTURAL BASIS FOR OCTAMERIC RING FORMATION AND DNATITL 2 INTERACTION OF THE HUMAN HOMOLOGOUS-PAIRING PROTEIN DMC1REF MOL.CELL V. 14 363 2004REFN ISSN 1097-2765PMID 15125839DOI 10.1016/S1097-2765(04)00218-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 1v5w DMC1 crystal structure of the human dmc1 protein 3.2Å AUTH T.KINEBUCHI,W.KAGAWA,R.ENOMOTO,K.TANAKA,K.MIYAGAWA,AUTH 2 T.SHIBATA,H.KURUMIZAKA,S.YOKOYAMATITL STRUCTURAL BASIS FOR OCTAMERIC RING FORMATION AND DNATITL 2 INTERACTION OF THE HUMAN HOMOLOGOUS-PAIRING PROTEIN DMC1REF MOL.CELL V. 14 363 2004REFN ISSN 1097-2765PMID 15125839DOI 10.1016/S1097-2765(04)00218-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2ct2 TRIM32 solution structure of the ring domain of the tripartite motif protein 32 -1.0Å AUTH K.MIYAMOTO,N.TOCHIO,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THETITL 2 TRIPARTITE MOTIF PROTEIN 32REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4bhw EP300 structural basis for autoinhibition of the acetyltransferase activity of p300 2.8Å AUTH M.DELVECCHIO,J.GAUCHER,C.AGUILAR-GURRIERI,E.ORTEGA,D.PANNETITL STRUCTURE OF THE P300 CATALYTIC CORE AND IMPLICATIONS FORTITL 2 CHROMATIN TARGETING AND HAT REGULATIONREF NAT.STRUCT.MOL.BIOL. V. 20 1040 2013REFN ISSN 1545-9993PMID 23934153DOI 10.1038/NSMB.2642 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3naf KCNMA1 structure of the intracellular gating ring from the human high- conductance ca2+ gated k+ channel (bk channel) 3.1Å AUTH Y.WU,Y.YANG,S.YE,Y.JIANGTITL STRUCTURE OF THE GATING RING FROM THE HUMANTITL 2 LARGE-CONDUCTANCE CA(2+)-GATED K(+) CHANNEL.REF NATURE V. 466 393 2010REFN ISSN 0028-0836PMID 20574420DOI 10.1038/NATURE09252 Variant Set Distributions Ripley’s K Analysis Plots Variant […]