Assessment of Structural Intolerance and Durability
General Structure Information 2dmk MID2 the solution structure of the fn3 domain of human midline 2 protein -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE FN3 DOMAIN OF HUMANTITL 2 MIDLINE 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wil KIAA1045 solution structure of the ring finger domain of the human kiaa1045 protein -1.0Å AUTH K.MIYAMOTO,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING FINGER DOMAIN OFTITL 2 THE HUMAN KIAA1045 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3rip TUBGCP4 crystal structure of human gamma-tubulin complex protein 4 (gcp4) 2.3Å AUTH V.GUILLET,M.KNIBIEHLER,L.GREGORY-PAURON,M.H.REMY,C.CHEMIN,AUTH 2 B.RAYNAUD-MESSINA,C.BON,J.M.KOLLMAN,D.A.AGARD,A.MERDES,AUTH 3 L.MOUREYTITL CRYSTAL STRUCTURE OF GAMMA-TUBULIN COMPLEX PROTEIN GCP4TITL 2 PROVIDES INSIGHT INTO MICROTUBULE NUCLEATION.REF NAT.STRUCT.MOL.BIOL. V. 18 915 2011REFN ISSN 1545-9993PMID 21725292DOI 10.1038/NSMB.2083 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 1z6u UHRF2 np95-like ring finger protein isoform b [homo sapiens] 2.1Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,E.M.NEWMAN,AUTH 2 F.MACKENZIE,M.SUNDSTROM,C.ARROWSMITH,A.EDWARDS,AUTH 3 A.BOCHKAREV,S.DHE-PAGANON,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL 2.1 ANGSTROM CRYSTAL STRUCTURE OF THE HUMANTITL 2 UBIQUITIN LIAGSE NIRFREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2db8 TRIM9 solution structures of the fn3 domain of human tripartite motif protein 9 -1.0Å AUTH M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 TRIPARTITE MOTIF PROTEIN 9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2yrg TRIM5 solution structure of the b-box domain from tripartite motif-containing protein 5 -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE B-BOX DOMAIN FROMTITL 2 TRIPARTITE MOTIF-CONTAINING PROTEIN 5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wy8 UHRF2 solution structure of the n-terminal ubiquitin-like domain in human np95/icbp90-like ring finger protein (nirf) -1.0Å AUTH C.ZHAO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINALTITL 2 UBIQUITIN-LIKE DOMAIN IN HUMAN NP95/ICBP90-LIKETITL 3 RING FINGER PROTEIN (NIRF)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1jm7 BARD1 solution structure of the brca1/bard1 ring-domain heterodimer -1.0Å AUTH P.S.BRZOVIC,P.RAJAGOPAL,D.W.HOYT,M.C.KING,AUTH 2 R.E.KLEVITTITL STRUCTURE OF A BRCA1-BARD1 HETERODIMERIC RING-RINGTITL 2 COMPLEX.REF NAT.STRUCT.BIOL. V. 8 833 2001REFN ISSN 1072-8368PMID 11573085DOI 10.1038/NSB1001-833 Variant Set Distributions Mapped Variants
General Structure Information 4ljq RNF31 crystal structure of the catalytic core of e3 ligase hoip 2.45Å AUTH B.STIEGLITZ,R.R.RANA,M.G.KOLIOPOULOS,A.C.MORRIS-DAVIES,AUTH 2 V.SCHAEFFER,E.CHRISTODOULOU,S.HOWELL,N.R.BROWN,I.DIKIC,AUTH 3 K.RITTINGERTITL STRUCTURAL BASIS FOR LIGASE-SPECIFIC CONJUGATION OF LINEARTITL 2 UBIQUITIN CHAINS BY HOIP.REF NATURE V. 503 422 2013REFN ISSN 0028-0836PMID 24141947DOI 10.1038/NATURE12638 Variant Set Distributions Mapped Variants
General Structure Information 2csz SYTL4 solution structure of the ring domain of the synaptotagmin- like protein 4 -1.0Å AUTH K.MIYAMOTO,M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THETITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants