General Structure Information
| PDB ID | 3rip |
| HGNC Gene Label(s) | TUBGCP4 |
| Structure Name | crystal structure of human gamma-tubulin complex protein 4 (gcp4) |
| Resolution | 2.3Å |
| Reference | AUTH V.GUILLET,M.KNIBIEHLER,L.GREGORY-PAURON,M.H.REMY,C.CHEMIN,AUTH 2 B.RAYNAUD-MESSINA,C.BON,J.M.KOLLMAN,D.A.AGARD,A.MERDES,AUTH 3 L.MOUREYTITL CRYSTAL STRUCTURE OF GAMMA-TUBULIN COMPLEX PROTEIN GCP4TITL 2 PROVIDES INSIGHT INTO MICROTUBULE NUCLEATION.REF NAT.STRUCT.MOL.BIOL. V. 18 915 2011REFN ISSN 1545-9993PMID 21725292DOI 10.1038/NSMB.2083 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 568 |
| Number Of SNVs | 106 |
| Number Of Permutations | 48043 |
| Optimal Distance Threshold | 46.0 |
| K Statistic | 0.481 |
| p-value | 0.076 |
COSMIC
| Number Of Residues | 568 |
| Number Of SNVs | 11 |
| Number Of Permutations | 11591 |
| Optimal Distance Threshold | 65.0 |
| K Statistic | 0.509 |
| p-value | 0.235 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 106 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 65.0 |
| K Statistic | -0.158 |
| p-value | 0.244 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
