Assessment of Structural Intolerance and Durability
General Structure Information 2ka4 STAT2 nmr structure of the cbp-taz1/stat2-tad complex -1.0Å AUTH J.M.WOJCIAK,M.A.MARTINEZ-YAMOUT,H.J.DYSON,AUTH 2 P.E.WRIGHTTITL STRUCTURAL BASIS FOR RECRUITMENT OF CBP/P300TITL 2 COACTIVATORS BY STAT1 AND STAT2 TRANSACTIVATIONTITL 3 DOMAINSREF EMBO J. V. 28 948 2009REFN ISSN 0261-4189PMID 19214187DOI 10.1038/EMBOJ.2009.30 Variant Set Distributions Mapped Variants
General Structure Information 2kg1 HNRNPF structure of the third qrrm domain of hnrnp f in complex with a agggau g-tract rna -1.0Å AUTH C.DOMINGUEZ,J.F.FISETTE,B.CHABOT,F.H.ALLAINTITL STRUCTURAL BASIS OF G-TRACT RECOGNITION AND ENCAGING BYTITL 2 HNRNP F QUASI-RRMS.REF NAT.STRUCT.MOL.BIOL. V. 17 853 2010REFN ISSN 1545-9993PMID 20526337DOI 10.1038/NSMB.1814 Variant Set Distributions Mapped Variants
General Structure Information 2eao EPHB1 solution structure of the c-terminal sam-domain of mouse ephrin type-b receptor 1 precursor (ec 2.7.1.112) -1.0Å AUTH A.K.GORONCY,M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL SAM-DOMAIN OFTITL 2 MOUSE EPHRIN TYPE-B RECEPTOR 1 PRECURSOR (ECTITL 3 2.7.1.112)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1nvp GTF2A1 human tfiia/tbp/dna complex 2.1Å AUTH M.BLEICHENBACHER,S.TAN,T.J.RICHMONDTITL NOVEL INTERACTIONS BETWEEN THE COMPONENTS OF HUMANTITL 2 AND YEAST TFIIA/TBP/DNA COMPLEXES.REF J.MOL.BIOL. V. 332 783 2003REFN ISSN 0022-2836PMID 12972251DOI 10.1016/S0022-2836(03)00887-8 Variant Set Distributions Mapped Variants
General Structure Information 3eto NOTCH1 2 angstrom xray structure of the notch1 negative regulatory region (nrr) 2.0Å AUTH W.R.GORDON,M.ROY,D.VARDAR-ULU,M.GARFINKEL,M.R.MANSOUR,AUTH 2 J.C.ASTER,S.C.BLACKLOWTITL STRUCTURE OF THE NOTCH1-NEGATIVE REGULATORY REGION:TITL 2 IMPLICATIONS FOR NORMAL ACTIVATION AND PATHOGENIC SIGNALINGTITL 3 IN T-ALL.REF BLOOD V. 113 4381 2009REFN ISSN 0006-4971PMID 19075186DOI 10.1182/BLOOD-2008-08-174748 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3h95 NUDT6 crystal structure of the nudix domain of nudt6 1.7Å AUTH L.TRESAUGUES,M.MOCHE,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTYENOVA,A.KOTZCH,T.K.NIELSEN,T.NYMAN,C.PERSSON,AUTH 5 J.SAGEMARK,H.SCHUELER,P.SCHUTZ,M.I.SIPONEN,L.SVENSSON,AUTH 6 A.G.THORSELL,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE NUDIX DOMAIN OF NUDT6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fxt NUDT6 crystal structure of the n-terminal domain of human nudt6 2.3Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,L.LEHTIO,M.MOCHE,M.E.NILSSON,T.NYMAN,C.PERSSON,AUTH 5 J.SAGEMARK,H.SCHUELER,M.I.SIPONEN,A.G.THORSELL,AUTH 6 S.VAN DEN BERG,J.WEIGELT,M.WIKSTROM,M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN NUDT6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1cmz RGS19 solution structure of gaip (galpha interacting protein): a regulator of g protein signaling -1.0Å AUTH E.DE ALBA,L.DE VRIES,M.G.FARQUHAR,N.TJANDRATITL SOLUTION STRUCTURE OF HUMAN GAIP (GALPHATITL 2 INTERACTING PROTEIN): A REGULATOR OF G PROTEINTITL 3 SIGNALING.REF J.MOL.BIOL. V. 291 927 1999REFN ISSN 0022-2836PMID 10452897DOI 10.1006/JMBI.1999.2989 Variant Set Distributions Mapped Variants
General Structure Information 2jri ATXN3 solution structure of the josephin domain of ataxin-3 in complex with ubiquitin molecule. -1.0Å AUTH G.NICASTRO,R.MENON,L.MASINO,A.PASTORETITL UNDERSTANDING THE PLASTICITY OF THETITL 2 UBIQUITIN-PROTEIN RECOGNITION CODE: THE JOSEPHINTITL 3 DOMAIN OF ATAXIN-3 IS A DIUBIQUITIN BINDING MOTIFREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2l7z HOXA13 nmr structure of a13 homedomain -1.0Å AUTH Y.ZHANG,C.A.LARSEN,H.S.STADLER,J.B.AMESTITL STRUCTURAL BASIS FOR SEQUENCE SPECIFIC DNA BINDING ANDTITL 2 PROTEIN DIMERIZATION OF HOXA13.REF PLOS ONE V. 6 23069 2011REFN ESSN 1932-6203PMID 21829694DOI 10.1371/JOURNAL.PONE.0023069 Variant Set Distributions Mapped Variants