General Structure Information
| PDB ID | 2jri |
| HGNC Gene Label(s) | ATXN3 |
| Structure Name | solution structure of the josephin domain of ataxin-3 in complex with ubiquitin molecule. |
| Resolution | -1.0Å |
| Reference | AUTH G.NICASTRO,R.MENON,L.MASINO,A.PASTORETITL UNDERSTANDING THE PLASTICITY OF THETITL 2 UBIQUITIN-PROTEIN RECOGNITION CODE: THE JOSEPHINTITL 3 DOMAIN OF ATAXIN-3 IS A DIUBIQUITIN BINDING MOTIFREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 182 |
| Number Of SNVs | 33 |
| Number Of Permutations | 18285 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.273 |
| p-value | 0.027 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.317 |
| p-value | 0.049 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
