Assessment of Structural Intolerance and Durability
General Structure Information 2kdb HERPUD2 solution structure of human ubiquitin-like domain of herpud2_9_85, northeast structural genomics consortium (nesg) target ht53a -1.0Å AUTH R.DOHERTY,B.WU,C.FARES,A.LEMAK,A.GUTMANAS,A.SEMESI,A.YEE,AUTH 2 C.H.ARROWSMITH,S.DHE-PAGANONTITL STRUCTURE OF HUMAN HOMOCYSTEINE-INDUCIBLE, ENDOPLASMICTITL 2 RETICULUM STRESS-INDUCIBLE, UBIQUITIN-LIKE DOMAIN MEMBER 2TITL 3 (HERPUD2 OR HERP)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jrf TPPP3 solution nmr structure of tubulin polymerization-promoting protein family member 3 from homo sapiens. northeast structural genomics target hr387. -1.0Å AUTH J.M.ARAMINI,P.ROSSI,R.SHASTRY,C.NWOSU,K.CUNNINGHAM,AUTH 2 R.XIAO,J.LIU,M.C.BARAN,P.K.RAJAN,T.B.ACTON,B.ROST,AUTH 3 G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF TUBULINTITL 2 POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3TITL 3 FROM HOMO SAPIENS.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3bl7 DCPS synthetic gene encoded dcps bound to inhibitor dg156844 2.31Å AUTH J.SINGH,M.SALCIUS,S.W.LIU,B.L.STAKER,R.MISHRA,AUTH 2 J.THURMOND,G.MICHAUD,D.R.MATTOON,J.PRINTEN,AUTH 3 J.CHRISTENSEN,J.M.BJORNSSON,B.A.POLLOK,M.KILEDJIAN,AUTH 4 L.STEWART,J.JARECKI,M.E.GURNEYTITL DCPS AS A THERAPEUTIC TARGET FOR SPINAL MUSCULARTITL 2 ATROPHY.REF ACS CHEM.BIOL. V. 3 711 2008REFN ISSN 1554-8929PMID 18839960DOI 10.1021/CB800120T Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3c9q WDYHV1 crystal structure of the uncharacterized human protein c8orf32 with bound peptide 1.5Å AUTH E.BITTO,C.A.BINGMAN,J.G.MCCOY,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF THE UNCHARACTERIZED HUMAN PROTEINTITL 2 C8ORF32 WITH BOUND PEPTIDE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l0a STAM solution nmr structure of signal transducing adapter molecule 1 stam-1 from homo sapiens, northeast structural genomics consortium target hr4479e -1.0Å AUTH Y.TANG,H.JANJUA,C.CICCOSANTI,R.SHASTRY,B.ROST,T.B.ACTON,AUTH 2 R.XIAO,J.K.EVERETT,G.T.MONTELIONE,C.H.ARROWSMITHTITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4479EREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2r0b STYX crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein 1.6Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,T.P.DILORENZO,AUTH 2 V.MALASHKEVICH,S.R.WASSERMAN,S.SWAMINATHAN,S.ESWARAMOORTHY,AUTH 3 R.AGARWAL,D.KUMARAN,M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,AUTH 4 J.ALVARADO,U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 5 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Mapped Variants
General Structure Information 2l0b PJA1 solution nmr structure of zinc finger domain of e3 ubiquitin-protein ligase praja-1 from homo sapiens, northeast structural genomics consortium (nesg) target hr4710b -1.0Å AUTH G.LIU,S.TONG,R.XIAO,T.B.ACTON,J.K.EVERETT,G.T.MONTELIONETITL SOLUTION STRUCTURE OF ZINC FINGER DOMAIN OF E3TITL 2 UBIQUITIN-PROTEIN LIGASE PROTEIN PRAJA-1 FROM HOMO SAPIENS,TITL 3 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGETTITL 4 HR4710BREF […]
General Structure Information 2jxx NFATC2IP nmr solution structure of ubiquitin-like domain of nfatc2ip. northeast structural genomics consortium target hr5627 -1.0Å AUTH R.S.DOHERTY,S.DHE-PAGANON,C.FARES,A.LEMAK,C.BUTLER,AUTH 2 S.SRISAILAM,M.KARRA,A.YEE,J.WEIGELT,A.M.EDWARDS,AUTH 3 C.H.ARROWSMITHTITL SOLUTION STRUCTURE OF UBIQUITIN-LIKE DOMAIN OFTITL 2 NFATC2IP.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bvo HSCB crystal structure of human co-chaperone protein hscb 3.0Å AUTH E.BITTO,C.A.BINGMAN,L.BITTOVA,D.A.KONDRASHOV,R.M.BANNEN,AUTH 2 B.G.FOX,J.L.MARKLEY,G.N.PHILLIPSTITL STRUCTURE OF HUMAN J-TYPE CO-CHAPERONE HSCB REVEALS ATITL 2 TETRACYSTEINE METAL-BINDING DOMAIN.REF J.BIOL.CHEM. V. 283 30184 2008REFN ISSN 0021-9258PMID 18713742DOI 10.1074/JBC.M804746200 Variant Set Distributions Mapped Variants