General Structure Information
| PDB ID | 2jrf |
| HGNC Gene Label(s) | TPPP3 |
| Structure Name | solution nmr structure of tubulin polymerization-promoting protein family member 3 from homo sapiens. northeast structural genomics target hr387. |
| Resolution | -1.0Å |
| Reference | AUTH J.M.ARAMINI,P.ROSSI,R.SHASTRY,C.NWOSU,K.CUNNINGHAM,AUTH 2 R.XIAO,J.LIU,M.C.BARAN,P.K.RAJAN,T.B.ACTON,B.ROST,AUTH 3 G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF TUBULINTITL 2 POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3TITL 3 FROM HOMO SAPIENS.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 176 |
| Number Of SNVs | 50 |
| Number Of Permutations | 11976 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.048 |
| p-value | 0.664 |
COSMIC
| Number Of Residues | 176 |
| Number Of SNVs | 4 |
| Number Of Permutations | 539 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.167 |
| p-value | 0.315 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.517 |
| p-value | 0.037 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
